Survival of Patients With Cystic Fibrosis

Cystic fibrosis: current survival and population estimates to the year 2000.

“…5 The improvement in survival is likely to continue over the next decade with improved medical care and increased availability ofheartlung transplantation. Our predictions of median survival for future cohorts were very sensitive to the model used, so we have reported our estimates only up to the present birth cohort.…”

Role of epithelial nitric oxide in airway viral infection

“…Clinical epidemiology suggests that virus infections impact on early morbidity and tempo of disease progression in CF. In fact, although extension of CF children's life expectancy occurred with the introduction of antibiotics, vaccination against virus such as measles was one of the earliest interventions that led to improved survival in the 1960s [143]. Prior to viral vaccinations, CF neonates who contracted measles, a virus like HPIV3 in the paramyxovirus family, had progressive decline with worsening of pulmonary infections and early death [144,145].…”

Effects of social class, sex, and region of residence on age at death from cystic fibrosis.

“…Concentrations of total triglyceride (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11) (0-14) v 0*68 (0.08) mmol/l), very low density lipoprotein triglyceride (0-56 (0.10) v 0 30 (0.05) mmol/l), apolipoprotein B (0-88 (0.06) v 0-67 (0 03) g/l) and fibrinogen (2-2 (0 1) v 1-9 (0-1) g/W), and diastolic arterial pressure (80 (2) v 74 (2) mm Hg), were also higher in patients with microalbuminuria.…”