Survival of Severe Acute Respiratory Syndrome Coronavirus

Lai, Mary Y.Y.; Cheng, Peter K.C.; Lim, Wilina

doi:10.1086/433186

Cited by 308 publications

(283 citation statements)

References 10 publications

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“…Loss of microbial viability due to drying is well documented (Gerba & Kennedy, 2007;Lai et al, 2005;Stowell et al, 2012;Xie et al, 2006); generally, enveloped viruses and Gram negative bacteria tend to lose viability at a faster rate than non-enveloped viruses, Gram positive bacteria, and bacterial spores. Data show minimal loss of viability for S. aureus, Adenovirus, and B. atrophaeus spores while E. coli and Vesicular stomatitis virus lost over 1 log 10 after an hour of drying under ambient laboratory conditions.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of a Dry Fogging System for Laboratory Decontamination

et al. 2012

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Section: Discussionmentioning

confidence: 99%

Evaluation of a Dry Fogging System for Laboratory Decontamination

et al. 2012

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“…SARS-CoV has been shown to survive after drying on different kinds of materials or diluted in water, revealing a decreased infectivity only after 72 to 96 hrs, depending on the conditions. However, its infectivity is reduced more rapidly if it is deposited on porous surfaces such as cotton or paper [106,108]. …”

Section: Hcovs: Enveloped But Not That Fragilementioning

confidence: 99%

Human Coronaviruses: Insights into Environmental Resistance and Its Influence on the Development of New Antiseptic Strategies

Geller

Varbanov

Duval

2012

Viruses

390

374

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The Coronaviridae family, an enveloped RNA virus family, and, more particularly, human coronaviruses (HCoV), were historically known to be responsible for a large portion of common colds and other upper respiratory tract infections. HCoV are now known to be involved in more serious respiratory diseases, i.e. bronchitis, bronchiolitis or pneumonia, especially in young children and neonates, elderly people and immunosuppressed patients. They have also been involved in nosocomial viral infections. In 2002–2003, the outbreak of severe acute respiratory syndrome (SARS), due to a newly discovered coronavirus, the SARS-associated coronavirus (SARS-CoV); led to a new awareness of the medical importance of the Coronaviridae family. This pathogen, responsible for an emerging disease in humans, with high risk of fatal outcome; underline the pressing need for new approaches to the management of the infection, and primarily to its prevention. Another interesting feature of coronaviruses is their potential environmental resistance, despite the accepted fragility of enveloped viruses. Indeed, several studies have described the ability of HCoVs (i.e. HCoV 229E, HCoV OC43 (also known as betacoronavirus 1), NL63, HKU1 or SARS-CoV) to survive in different environmental conditions (e.g. temperature and humidity), on different supports found in hospital settings such as aluminum, sterile sponges or latex surgical gloves or in biological fluids. Finally, taking into account the persisting lack of specific antiviral treatments (there is, in fact, no specific treatment available to fight coronaviruses infections), the Coronaviridae specificities (i.e. pathogenicity, potential environmental resistance) make them a challenging model for the development of efficient means of prevention, as an adapted antisepsis-disinfection, to prevent the environmental spread of such infective agents. This review will summarize current knowledge on the capacity of human coronaviruses to survive in the environment and the efficacy of well-known antiseptic-disinfectants against them, with particular focus on the development of new methodologies to evaluate the activity of new antiseptic-disinfectants on viruses.

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“…These agents has been successfully used during many infectious disease outbreaks including SARS, EBOV, and influenza H1N1 to decontaminate hospital instruments, infectious materials, and personal protective equipment [20][21][22] for health care professionals. In the current West African EVD outbreak, a 0.5% chlorine solution has been recommended to disinfect surfaces contaminated with EBOV, and is now recommended for disinfection by the World Health Organization [23].…”

Section: Discussionmentioning

confidence: 99%

Inactivation of Human Rhinovirus due to Heat, UV Irradiation and Chemical Disinfectants

Wang¹,

Wang²,

Song³

et al. 2017

J Antivir Antiretrovir

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To evaluate and understand inactivation of HRV under many physical conditions and chemical agents, HRV86 were selected to expose with temperature, ultraviolet light (UV), Sodium hypochlorite, Virkon S, Peracetic acid (PAA), Glutaraldehyde and Ethanolin, respectively. The inactivation of HRV was analyzed by infectivity of the viral strains on the HeLa cells. Our research found the rhinovirus was very sensitive to temperature changes. Viral infectivity thoroughly lost after HRV86 was treated at 60°C for 10 min or UV irradiation for 45 min or longer. Virus also was completely inactivated after exposure to sodium hypochlorite (0.1 g/L) beyond 10 min, glutaraldehyde (10 g/L) for 5 min, Virkon-S (5 g/L) for 10 min, PAA (3 g/L) for 2 min, or 75% alcohol for 5 min or longer. The results provided the essential information for prevention and intervention of common cold.

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Survival of Severe Acute Respiratory Syndrome Coronavirus

Cited by 308 publications

References 10 publications

Evaluation of a Dry Fogging System for Laboratory Decontamination

Evaluation of a Dry Fogging System for Laboratory Decontamination

Human Coronaviruses: Insights into Environmental Resistance and Its Influence on the Development of New Antiseptic Strategies

Inactivation of Human Rhinovirus due to Heat, UV Irradiation and Chemical Disinfectants

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