Microorganisms are ubiquitous, including within habitats, and they have a negative impact on human health, sanitation, and living situations. Surface microbial load is affected by various factors such as location, usage, cleaning, and environment. Kitchen countertops, toilet fittings, doorknobs, electrical appliances, and fabrics can harbor bacteria, viruses, fungi, and archaea. These pathogens may originate from persons, air or external sources. It is known that high microbial loads on surfaces cause health hazards. Pathogenic bacteria can live for extended durations on surfaces, causing infections by contact or aerosolization. Surface microbial load can be decreased through cleaning and disinfection processes. Reducing microbiological contamination requires the use of appropriate cleaning products, and procedures. In antimicrobial coatings, silver ions and other disinfectants can inhibit surface bacterium adhesion and growth. To mitigate health risks, it is necessary to comprehend microbial colonization and survival on various surfaces. This article examines common surface bacteria, microbial load factors, transmission pathways, and their impact on human health.