Survival on Integrated Therapies—What Assumptions Shall We Make?

Wing, A. J.

doi:10.1016/s0272-6386(84)80097-9

Cited by 9 publications

(2 citation statements)

References 4 publications

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“…showing strong evidence of increased risk associated with such factors as age, presence of diabetes, ischemic heart disease, and cancer [2][3][4][5]7], The overall survival of patients in our sample, independent of treatment modality, is also similar to recent reports from this country [2], and is only slightly worse than the cumulated EDTA experience [14].…”

Section: Discussionsupporting

confidence: 82%

Survival in a Community Hospital Dialysis Center

Walker

Grove

1988

Am J Nephrol

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The survival experience of 213 patients with end-stage renal disease treated over a 10-year period in a community hospital dialysis center is the focus of the study. Statistical assessments of the effects of risk factors and alternative treatment modalities on patient survival are made using survival functions and proportional hazards regression models. Comparisons of the data base and the main results with those of previous published reports are presented. A key result is our finding of improved survival since the introduction of a continuous ambulatory peritoneal dialysis program in 1980. This result is discussed in some detail.

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Section: Discussionsupporting

confidence: 82%

Survival in a Community Hospital Dialysis Center

Walker

Grove

1988

Am J Nephrol

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“…The survival curve, therefore, has a 'better' appearance. The EDTA Registry has usually shown survival after grafting by considering all deaths occurring at any time after the event of transplantation [11]. This is depicted by the lower curve in Fig.…”

Section: Patient and Graft Survival After First Cadaveric Graftmentioning

confidence: 99%

Survival on Renal Replacement Therapy: Data from the EDTA Registry

Brunner

Broyer

Brynger

et al. 1988

Nephrology Dialysis Transplantation

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Abstract. Extensive survival data are presented from the EDTA Registry's files for patients who started renal replacement therapy in 1970-1974 compared to 1980-1984. The contribution of the different treatment modalities (haemodialysis, continuous peritoneal dialysis, and transplantation) to the survival of patients according to geographical region is also shown. Survival on renal replacement therapy, irrespective of treatment modality and of primary renal disease, was best in the 10-14-yearold patients, with 58% at 10 years and 52% at 15 years, and decreased with rising age to 28% at 10 years and 16% at 15 years in patients aged 45-54 when they commenced therapy in [1970][1971][1972][1973][1974]. When comparing the 0-4-year-old with the 10-14-year-old cohort of the paediatric patients, 5-year survival rates for patients starting renal replaceCorrespondence and offprint requests to: Prof. F. P. Brunner. European Dialysis and Transplant Association Registry. St Thomas' Hospital. London SE17EH.UK. ment therapy in the early eighties declined from 85% to 70% with decreasing age.Treatment policy, as reflected by the proportion of patients on different modes of therapy, varied markedly between European regions but affected survival to a small extent only. The large population with diabetic nephropathy incurred annual mortality rates 2-3 times greater than those observed in patients with 'standard' primary renal diseases. Haemodialysis and continuous peritoneal dialysis, although not comparable because of important differences in selection policy, yielded similar survival rates.Patient and graft survival rates have improved markedly when comparing patients starting renal replacement therapy in the early seventies with the eighties; particularly for cadaveric transplantation. Patient survival after second grafting was similar to that after first grafting, with 83% at 5 years after second cadaveric grafting in the 15-44-year-old cohort, vs 85% after first 110 cadaver transplantation in 1980-1984. Second cadaveric graft survival was superior to average first-graft survival for those recipients whose first graft had been functioning for more than 1 year. However, second-graft survival in rapid rejectors of a first graft as well as third cadaveric graft survival were curtailed by the large number of early losses, with only 52% of third grafts functioning at 1 year. For living related donor transplantation, parents were mostly used in children whilst identical siblings predominated in adults older than 45. In the early eighties, patient survival was 92% at 5 years for recipients younger than 15. 87% for the 15-45 year old cohort and 72% for those aged 45 or older. From the overall survival rates on renal replacement therapy obtained at 5 years in the early eighties, it appears safe to predict that at least 65% of young adults and 25% of patients aged 55-64 will be surviving at 10 years after starting therapy.

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Hemodialysis in the home and its impact on quality of life

Blagg¹

1999

Quality Assurance in Dialysis

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Survival on Integrated Therapies—What Assumptions Shall We Make?

Cited by 9 publications

References 4 publications

Survival in a Community Hospital Dialysis Center

Survival in a Community Hospital Dialysis Center

Survival on Renal Replacement Therapy: Data from the EDTA Registry

Hemodialysis in the home and its impact on quality of life

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