Survival outcomes of patients with temporal bone squamous cell carcinoma with different invasion patterns

Abstract

Patients with parotid gland, TMJ involvement, and previous middle ear surgery for chronic otitis media had poor outcomes.

Clinical Characteristics and Management of External Auditory Canal Squamous Cell Carcinoma in Post-Irradiated Nasopharyngeal Carcinoma Patients

“…Our data showed that the tumor differentiation did not correlate with the survival in T4 stage (31). However, Masterson's study indicated that histopathologic grade was a significant predictor of survival (32).…”

Update on Surgical Outcomes of Lateral Temporal Bone Resection for Ear and Temporal Bone Malignancies

“…6 Despite advances in the management of temporal bone malignancies, staging and prognostic predictors for tumors remain elusive. The Pittsburgh Staging Criteria proposed by Arriaga et al 7 in 1990 is widely utilized, and has been shown to correlate with prognosis in several retrospective studies, [8][9][10][11] although no significant correlation was observed in others. 11 In previous studies, obtaining negative margins as well as lymph node status have been shown to be important predictors of survival.…”

Correlation between the pathology and clinical presentations in patients with adenoid cystic carcinoma of the external auditory canal

“…In our series, in the 11 patients with otalgia, 5 (45%) had perineural invasion confirmed pathologically, whereas in the 16 patients with confirmed perineural invasion, only 5 (31%) complained of otalgia. In addition, our study demonstrated that no more patients with ACC of the external auditory canal complained of otalgia than those with squamous cell carcinoma of the external auditory canal in our previous study (38% vs 59%), in which the rate of facial nerve invasion was 43% . Given that otalgia can be caused not only by perineural invasion, but also by otitis externa, we assume that otalgia may be more related to local inflammation than perineural invasion.…”