Survival Rate of Short-Stem Hip Prostheses: A Comparative Analysis of Clinical Studies and National Arthroplasty Registers

Hauer, Georg; Vielgut, Ines; Amerstorfer, Florian; Maurer-Ertl, Werner; Leithner, Andreas; Sadoghi, Patrick

doi:10.1016/j.arth.2018.01.017

Cited by 38 publications

(33 citation statements)

References 14 publications

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“…We estimated a superiority of dependent clinical trials, as they may not be published if they do not meet the study designer's expectations and are usually conducted by experts in their field. However, this has not been observed and these findings appear to be consistent with results of previous investigators [11,18]. The amount of implanted prostheses in clinical studies is low compared to register data.…”

Section: Discussionsupporting

confidence: 88%

“…Methodologically, we analysed real life data and no "probabilities" and therefore no p values could be calculated as previously published [16]. Concerning the significance, we followed the criteria applied in previous investigations [10,11,18]. Significance was determined by deviations from the mean by a factor of three (for instance, the revision rates of a dataset are three times as high as in the control group).…”

Section: Discussionmentioning

confidence: 99%

“…As we have only included publications with more than 200 observed CY this might have caused a possible selection bias. However, an analysis of the revision rate per 100 observed CY is more appropriate with larger cohorts and long-term follow-up [18]. Furthermore, we compared the average revision rate per 100 observed CY from clinical studies with the CRR from arthroplasty registries.…”

Section: Discussionmentioning

confidence: 99%

“…All publications were investigated concerning "revision for any reason". To compare all included studies, which can differ in terms of included cases and investigated time periods, we calculated revisions per 100 observed component years (CY) which is widely accepted and has been applied repeatedly in the field of orthopaedics [9,11,[16][17][18]. Thereupon it is possible to compare different data sources regardless of their follow-up periods and number of UKAs.…”

Section: Outcome Measurementmentioning

confidence: 99%

See 3 more Smart Citations

Similar revision rates in clinical studies and arthroplasty registers and no bias for developer publications in unicompartmental knee arthroplasty

Hauer

Bernhardt

Hohenberger

et al. 2020

Arch Orthop Trauma Surg

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Purpose Our aim was to assess the outcome with respect to cumulative revision rates of unicompartmental knee arthroplasty (UKA) by comparing published literature and arthroplasty registry data. Our hypothesis was that there is a superior outcome of UKA described in dependent clinical studies compared to independent studies or arthroplasty registers. Methods A systematic review of all clinical studies on UKA in the past decade was conducted with the main endpoint revision rate. Revision rate was calculated as "revision per 100 component years (CY)". The respective data were analysed with regard to a potential difference of the percentage of performed revision surgeries as described in dependent and independent clinical studies. Clinical data were further compared to arthroplasty registers in a systematic search algorithm. Results In total, 48 study cohorts fulfilled our inclusion criteria and revealed 1.11 revisions per 100 CY. This corresponds to a revision rate of 11.1% after 10 years. No deviations with regard to revision rates for UKA among dependent and independent clinical literature were detected. Data from four arthroplasty registers showed lower survival rates after 10 years compared to published literature without being significant. Conclusions The outcomes of UKA in dependent and independent clinical studies do not differ significantly and are in line with arthroplasty register datasets. We cannot confirm biased results and the authors recommend the use of UKAs in properly selected patients by experts in their field.Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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Section: Discussionsupporting

confidence: 88%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Outcome Measurementmentioning

confidence: 99%

See 2 more Smart Citations

Similar revision rates in clinical studies and arthroplasty registers and no bias for developer publications in unicompartmental knee arthroplasty

Hauer

Bernhardt

Hohenberger

et al. 2020

Arch Orthop Trauma Surg

Self Cite

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“…if no early intervention is provided, ~80% of patients progress to femoral head collapse, hip dysfunction and permanent disability (14), and ultimately hip replacement becomes the only treatment option (13). However, postoperative infection, pain, functional rehabilitation, prosthetic replacement and other related complications (15)(16)(17)(18) result in vast economic burdens for patients and for society. The mechanism by which onFH develops remains unclear (19).…”

Section: Introductionmentioning

confidence: 99%

The potential roles of circular RNAs in osteonecrosis of the femoral head (Review)

Zhao

Wang

et al. 2019

Mol Med Report

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circular rnas (circrnas) are categorized as non-coding rnas that, unlike widely known canonical linear rnas, form a covalently closed continuous loop without 5' or 3' polarities, which enables them to resist digestion by rna exonucleases. although the functions of circrnas remain largely unknown, accumulated evidence has demonstrated that circrnas can act as microrna sponges, which allows them to regulate numerous biological processes and disease mechanisms, including apoptosis, angiogenesis, invasion, metastasis and stem cell differentiation. although research into circRNAs is in its infancy, studies have identified critical roles for circrnas in the initiation and progression of disease. The present study delineated the characteristics and functions of circrnas, and focused on the potential relationship between circrnas and osteonecrosis of the femoral head (onFH). circrnas represent a novel avenue for studying the mechanisms underlying onFH as well as possible treatments.

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Reproducing the Proximal Femur Anatomy Using Neck Anchorage Stem Design

Piriou

Sullivan

2020

Personalized Hip and Knee Joint Replacement

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Survival Rate of Short-Stem Hip Prostheses: A Comparative Analysis of Clinical Studies and National Arthroplasty Registers

Cited by 38 publications

References 14 publications

Similar revision rates in clinical studies and arthroplasty registers and no bias for developer publications in unicompartmental knee arthroplasty

Similar revision rates in clinical studies and arthroplasty registers and no bias for developer publications in unicompartmental knee arthroplasty

The potential roles of circular RNAs in osteonecrosis of the femoral head (Review)

Reproducing the Proximal Femur Anatomy Using Neck Anchorage Stem Design

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