This study reports the investigation of a degraded polyethylene insert retrieved after the catastrophic failure of a mobile bearing knee implant, occurred after a traumatic event and leading to a late revision. Understanding wear mechanisms of polyethylene components is important to improve the implants for joint replacement. This model of unicompartmental arthroplasty, due to its mobile, congruent insert and design, has the potential to attain low rates of wear, leading to an improved survival of the prosthesis over fixed-bearing knee implants. During the surgical technique, however, it is critical to avoid any source of impingement or incongruent articulation, as this are associated with increased rates of polyethylene wear and may contribute to the early necessity for revision surgery. The investigated insert presented a macroscopic fragmentation, surface and bulk defects and debris. Characterization of the retrieved polyethylene implant fragments was performed by macroscopic examination, by scanning electron microscopy and Fourier transform infrared spectroscopy. Due to a systematic retrieval analysis according to current standards, we can question that, in our case, third body wear is rarely pure bone or pure cement debris related but a combination of the two mentioned. The combination enhanced contribution of polyethylene debris in severe wear initiation and progression. Complete examination of the explants exhibiting breakage or severe wear may help in understanding pathogenic ways of failure in unicompartmental knee.