Susceptibility ofCampylobacter fetus subsp.jejuni to paromomycin

Freydière, Anne-Marie; Barbe, G; Gille, Y.; Vincent, P

doi:10.1007/bf01977485

Cited by 3 publications

(1 citation statement)

References 5 publications

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“…The enzyme acts on a substrate formed by an ester of 8 atoms of carbon conjugated with 4-MU, librating this last compound, which is strongly fluorescent and can be observed after 3-5 min under a UV lamp (wavelength, 366 nm). The development of a blue fluorescence over or around the colony was considered a positive result [9,[29][30][31][32][33][34][35].…”

Section: Introductionmentioning

confidence: 99%

Kinetics of catalyzed hydrolysis of 4-methylumbelliferyl caprylate (MUCAP) salmonella reagent

Al-Kady

Ahmed

Gaber

et al. 2011

Spectrochimica Acta Part A: Molecular and Biomolecular Spectros

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Section: Introductionmentioning

confidence: 99%

Kinetics of catalyzed hydrolysis of 4-methylumbelliferyl caprylate (MUCAP) salmonella reagent

Al-Kady

Ahmed

Gaber

et al. 2011

Spectrochimica Acta Part A: Molecular and Biomolecular Spectros

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In vitro Susceptibility of Campylobacter jejuni and Campylobacter coli Isolated in Austria to Erythromycin and Ciprofloxacin

Hirschl

Wolf²,

Berger

et al. 1990

Zentralblatt für Bakteriologie

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Susceptibility of Campylobacter jejuni and Campylobacter coli to macrolides and related compounds

Elharrif¹,

Mégraud²,

Marchand³

1985

Antimicrob Agents Chemother

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The susceptibility of 105 thermophilic campylobacters from human and swine origins to eight macrolides and related compounds was tested. Erythromycin, josamycin, clindamycin, and ASE 136 BS (a new erythromycin derivative) were the most active against the human strains. The swine strains were highly resistant, except to pristinamycin. The human Campylobacter coli strains (except for two strains) behaved like the C. jejuni strains.Campylobacterjejuni and, to a lesser extent, C. coli, are now recognized as a major cause of enteric infections of worldwide distribution. Treatment with an antibiotic shown to be effective in vitro can be of value in that it eradicates the campylobacters in the intestine and so prevents a relapse or cross contaminations (especially between children) or both. It also has an effect on the evolution of the disease. The main antibiotic currently used for this purpose is a macrolide, erythromycin, but few studies comparing erythromycin with the other macrolides have been performed. The aim of this study was to determine the susceptibility of C. jejini and C. coli to macrolides and the related compounds lincomycin, clindamycin, and pristinamycin as well as to a new compound, ASE 136 BS.Seventy-nine strains of human origin were tested: 55 C. jejuni and 24 C. coli isolated in France (32 strains), Vietnam (11 strains), the United States (6 strains), Australia (8 strains), and Hungary (22 strains). Twenty-six C. coli strains from swine origin isolated in France (20 strains) and the United States (6 strains) were also tested. All these strains were isolated from fecal samples on a selective medium except for those from Australia, which were isolated by a filtration technique.The strains were identified by the following characteristics: morphology, oxidase and catalase tests, and growth at 42°C in a microaerophilic atmosphere. The hippurate test was used to differentiate C. jejuni (hippurate positive) and C. coli (hippurate negative) (10 (MIC, . 128 p.g/ml) reacting like the swine C. coli strains. All the C. coli strains resistant at a high level were also resistant to josamycin, clindamycin, and ASE 136 BS, except for two: one was susceptible to clindamycin and ASE 136 BS, and the other was susceptible only to clindamycin.Pristinamycin seemed to have the same activity against all the strains, in contrast to the other compounds tested.We did not notice any special behavior for the human strains from different countries. The two highly resistant C. coli strains of human origin were from France.Data concerning the susceptibility of campylobacters to the macrolides or related compounds are scarce. All of the campylobacter-antibiotic studies included erythromycin, which is the most widely prescribed antibiotic for the treatment of campylobacter enteritis, and sometimes clindamycin, but not the others. This results of our study are in agreement with the fact that these two agents are among the most effective. Josamycin was found to be slightly superior to erythromycin, as [Lg/ml, whereas that ...

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Susceptibility ofCampylobacter fetus subsp.jejuni to paromomycin

Abstract: CorrespondenceEur. J. Clin. Microbiol.identification of the bacteria with satisfactory sensitivity and specificity. However, results still require confirmation by culture.

Cited by 3 publications

References 5 publications

Kinetics of catalyzed hydrolysis of 4-methylumbelliferyl caprylate (MUCAP) salmonella reagent

Kinetics of catalyzed hydrolysis of 4-methylumbelliferyl caprylate (MUCAP) salmonella reagent

In vitro Susceptibility of Campylobacter jejuni and Campylobacter coli Isolated in Austria to Erythromycin and Ciprofloxacin

Susceptibility of Campylobacter jejuni and Campylobacter coli to macrolides and related compounds

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