Susceptibility to Plasmodium Berghei in a Laboratory Population of Anopheles Atroparvus (Diptera: Culicidae) After the Introduction of Plasmodium-Refractory Genotypes

Káay, H. J. Van Der; Laarman, J. J.; Curtis, C. F.; Boorsma, E. G.; Seventer, H.A. van

doi:10.1093/jmedent/19.5.536

Cited by 3 publications

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“…Following termination of the release program, the susceptibility of the population remained at half its original level, indicating recombination of genes for refractoriness with those for fitness (49). Similar results were obtained with a caged population of Anopheles atroparvus that was susceptible to Plasmodium berghei berghei, by introduction of males from a line that had low susceptibility to this malaria parasite (172).…”

Section: Potential Uses Of Refractory and Susceptible Coloniessupporting

confidence: 61%

Genetic variation in arthropod vectors of disease-causing organisms: obstacles and opportunities.

Gooding

1996

Clinical Microbiology Reviews

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Section: Potential Uses Of Refractory and Susceptible Coloniessupporting

confidence: 61%

Genetic variation in arthropod vectors of disease-causing organisms: obstacles and opportunities.

Gooding

1996

Clinical Microbiology Reviews

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Allozyme variation in Anopheles stephensi Liston from Pakistan (Diptera: Culicidae)

1987

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Allozyme variability was analyzed at 16 loci in 11 lines of Anopheles stephensi Liston from Pakistan. Six lines were considered as samples from natural populations. For these lines the mean number of alleles was 1.31-1.63, the degree of polymorphism was 0.188-0.375, the observed heterozygosity was 0.065-0.086, and the genetic distance ranged from 0.001 to 0.016. No population-specific alleles were found. Interbreeding was considerable (mean Fit = 0.183). Differences in allele frequencies were due considerable (mean Fit = 0.183). Differences in allele frequencies were due primarily to local inbreeding (Fis greater than Fst at most loci). The Lahore line, reared for more than 20 generations, had more homozygotes than the other lines. A line refractory to Plasmodium falciparum and a genetic sexing line exhibited decreased allozyme variability. The latter line showed reduced staining intensity at 10 loci. Linkage studies are recommended for the following loci with rare alleles: Acp, Gapdh, Icd-1, Icd-2, Mpi, and Pgd.

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Genetic variation in arthropod vectors of disease-causing organisms: obstacles and opportunities

Gooding

1996

Clin Microbiol Rev

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An overview of the genetic variation in arthropods that transmit pathogens to vertebrates is presented, emphasizing the genetics of vector-pathogen relationships and the biochemical genetics of vectors. Vector-pathogen interactions are reviewed briefly as a prelude to a discussion of the genetics of susceptibility and refractoriness in vectors. Susceptibility to pathogens is controlled by maternally inherited factors, sex-linked dominant alleles, and dominant and recessive autosomal genes. There is widespread interpopulation (including intercolony) and temporal variation in susceptibility to pathogens. The amount of biochemical genetic variation in vectors is similar to that found in other invertebrates. However, the amount varies widely among species, among populations within species, and temporally within populations. Biochemical genetic studies show that there is considerable genetic structuring of many vectors at the local, regional, and global levels. It is argued that genetic variation in vectors is critical in understanding vector-pathogen interactions and that genetic variation in vectors creates both obstacles to and opportunities for application of genetic techniques to the control of vectors.

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Susceptibility to Plasmodium Berghei in a Laboratory Population of Anopheles Atroparvus (Diptera: Culicidae) After the Introduction of Plasmodium-Refractory Genotypes

Cited by 3 publications

References 0 publications

Genetic variation in arthropod vectors of disease-causing organisms: obstacles and opportunities.

Genetic variation in arthropod vectors of disease-causing organisms: obstacles and opportunities.

Allozyme variation in Anopheles stephensi Liston from Pakistan (Diptera: Culicidae)

Genetic variation in arthropod vectors of disease-causing organisms: obstacles and opportunities

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