Susceptibility weighted imaging in the evaluation of movement disorders

Characterizing brain mineral deposition in patients with Wilson disease using susceptibility-weighted imaging

“…Since copper is paramagnetic, the observed abnormalities may indicate copper deposition. [13] These signal abnormalities can be also correlated with the paramagnetic effect of iron. [1] However, no correlations were observed between the copper content and CP values in our series.…”

Differentiating multiple-system atrophy from Parkinson's disease

“…10 The differentiating regions are the posterior regions of the putamen and pulvinar thalamus in which there is a higher iron-deposition pattern observed in MSA (Fig 1). 10,13,14 Increased nigral iron deposition is correlated with increasing severity of extrapyramidal motor symptoms in PD. 15 Quantifiable measurements of iron deposition using SWI phase-shift values in the substantia nigra were found to have a positive correlation with the unified Parkinson's disease rating scale motor score.…”

Wilson's disease patient with iron metabolism discharge barriers: A case report

“…Furthermore, it is an important and novel method for detecting abnormal iron metabolism in a high-risk population (11,16). WD patients are known to have an abnormal copper metabolism but whether they also have iron metabolism abnormalities has not yet been determined (17).…”