Susceptibility-weighted MR imaging to improve the specificity of erosion detection: a prospective feasibility study in hand arthritis

Ulas, Sevtap Tugce; Diekhoff, Torsten; Hermann, Kay-Geert A.; Poddubnyy, Denis; Hamm, Bernd; Makowski, Marcus R.

doi:10.1007/s00256-018-3116-0

Cited by 15 publications

(15 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Statistical analysis was performed using SPSS (V.27.0.0.0). 6 While other novel MRI sequences such as volumetric interpolated breath-hold examination (VIBE) and MRI-based synthetic CT have been shown to be superior to T1 in detecting erosions in the SIJ, [9][10][11] they do not allow direct visualisation of the cortical and trabecular bone structure and, thus, still suffer from typical MRI shortfalls. VIBE, for example, is a gradient echo sequence with an undesired T2* effect that causes a signal loss in the vicinity of calcium crystals, resulting in the typical stark contrast of soft tissue and bone.…”

Section: Discussionmentioning

confidence: 99%

“…One of them, susceptibility-weighted imaging (SWI), 5 has been successfully applied to erosion detection in patients with peripheral arthritis. 6 SWI depicts calcium structures directly by detecting and quantifying small magnetic field inhomogeneities surrounding calcium atoms. While SWI has been standard in many brain MRI protocols for several years, its transfer to musculoskeletal imaging was rather recent.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

CT-like images of the sacroiliac joint generated from MRI using susceptibility-weighted imaging (SWI) in patients with axial spondyloarthritis

et al. 2021

Self Cite

View full text Add to dashboard Cite

BackgroundTo analyse the added value of susceptibility-weighted imaging (SWI) compared with standard T1-weighted (T1) MRI for detecting structural lesions of the sacroiliac joint (SIJ) in patients with axial spondyloarthritis (axSpA) using CT as reference standard.Material and methodsSixty-eight patients with suspected or proven axSpA underwent both MRI and CT of the SIJ on the same day. Two readers separately scored CT, T1 and SWI for the presence of erosions, sclerosis and joint space changes using an established 24-region SIJ model. Disagreement was resolved by a third reader. Diagnostic accuracy (McNemar test), Cohen’s kappa (k), sensitivity (SE) and specificity were calculated on the joint level using CT as reference.ResultsIn CT, 38 joints showed erosions, 67 sclerosis and 37 joint space changes. Agreement with CT for erosions was 92.6% (k=0.811 (0.7–0.92)) in SWI and 87.5% (k=0.682 (0.54–0.82)) in T1 (p=0.143) and agreement for sclerosis 84.6% (k=0.69 (0.57–0.81)) and 62.5% (k=0.241 (0.13–0.35)) (p<0.001), respectively. This resulted in superior SE of SWI (81.6% vs 73.7%) for erosions and sclerosis (74.6% vs 23.9%) at a minor expense of SP. No differences were detected for joint space changes.ConclusionIn patients with axSpA, SWI depicts erosions and sclerosis more accurately than T1 spin echo MRI at 1.5 T.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

CT-like images of the sacroiliac joint generated from MRI using susceptibility-weighted imaging (SWI) in patients with axial spondyloarthritis

et al. 2021

Self Cite

View full text Add to dashboard Cite

show abstract

“…Their combinations might be non-specific or complex to interpret. Furthermore, MR is prone to artefacts in bone marrow that might mimic erosions and, thus, lead to false-positive interpretation 12 while other changes such as sclerosis can mask other important lesions. Therefore, specific definitions must be established and followed when reading MR. 13 Previous studies have already shown that MR is superior to radiography in detecting structural changes 3 and can be improved further by using more sophisticated pulse sequences that generate images with greater tissue contrast 7 8 or CT-like images.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Choose wisely: imaging for diagnosis of axial spondyloarthritis

et al. 2021

Self Cite

View full text Add to dashboard Cite

ObjectiveTo assess the diagnostic accuracy of radiography (X-ray, XR), CT and MRI of the sacroiliac joints for diagnosis of axial spondyloarthritis (axSpA).Methods163 patients (89 with axSpA; 74 with degenerative conditions) underwent XR, CT and MR. Three blinded experts categorised the imaging findings into axSpA, other diseases or normal in five separate reading rounds (XR, CT, MR, XR +MR, CT +MR). The clinical diagnosis served as reference standard. Sensitivity and specificity for axSpA and inter-rater reliability were compared.ResultsXR showed lower sensitivity (66.3%) than MR (82.0%) and CT (76.4%) and also an inferior specificity of 67.6% vs 86.5% (MR) and 97.3% (CT). XR +MR was similar to MR alone (sensitivity 77.5 %/specificity 87.8%) while CT+MR was superior (75.3 %/97.3%). CT had the best inter-rater reliability (kappa=0.875), followed by MR (0.665) and XR (0.517). XR +MR was similar (0.662) and CT+MR (0.732) superior to MR alone.ConclusionsXR had inferior diagnostic accuracy and inter-rater reliability compared with cross-sectional imaging. MR alone was similar in diagnostic performance to XR+MR. CT had the best accuracy, strengthening the importance of structural lesions for the differential diagnosis in axSpA.

show abstract

“…Artifact-related pseudoerosions were mentioned in 18 original papers and reviews and may be caused due to (1) partial volume artifacts of cross-sectional images or other modality-specific artifacts (ultrasound diffraction or reflection, insufficient fat suppression with MRI), or (2) a low signal-to-noise ratio ( Table 2) [1,5,52,[57][58][59][60][61][62][63][64][65][66][67][68].…”

Section: Artifact-related Pesudoerosionsmentioning

confidence: 99%

Pseudoerosions of Hands and Feet in Rheumatoid Arthritis: Anatomic Concepts and Redefinition

Hirtler

Rath

Platzgummer

et al. 2019

JCM

View full text Add to dashboard Cite

Rheumatoid arthritis is a chronic inflammatory disease characterized by the development of osseous and cartilaginous damage. The correct differentiation between a true erosion and other entities—then often called “pseudoerosions”—is essential to avoid misdiagnosing rheumatoid arthritis and to correctly interpret the progress of the disease. The aims of this systematic review were as follows: to create a definition and delineation of the term “pseudoerosion”, to point out morphological pitfalls in the interpretation of images, and to report on difficulties arising from choosing different imaging modalities. A systematic review on bone erosions in rheumatoid arthritis was performed based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The following search terms were applied in PubMed and Scopus: “rheumatoid arthritis”, “bone erosion”, “ultrasonography”, “radiography”, “computed tomography” and “magnetic resonance imaging”. Appropriate exclusion criteria were defined. The systematic review registration number is 138826. The search resulted ultimately in a final number of 25 papers. All indications for morphological pitfalls and difficulties utilizing imaging modalities were recorded and summarized. A pseudoerosion is more than just a negative definition of an erosion; it can be anatomic (e.g., a normal osseous concavity) or artefact-related (i.e., an artificial interruption of the calcified zones). It can be classified according to their configuration, shape, content, and can be described specifically with an anatomical term. “Calcified zone” is a term to describe the deep components of the subchondral, subligamentous and subtendinous bone, and may be applied for all non-cancellous borders of a bone, thus representing a third type of the bone matrix beside the cortical and the trabecular bone.

show abstract

Susceptibility-weighted MR imaging to improve the specificity of erosion detection: a prospective feasibility study in hand arthritis

Cited by 15 publications

References 32 publications

CT-like images of the sacroiliac joint generated from MRI using susceptibility-weighted imaging (SWI) in patients with axial spondyloarthritis

CT-like images of the sacroiliac joint generated from MRI using susceptibility-weighted imaging (SWI) in patients with axial spondyloarthritis

Choose wisely: imaging for diagnosis of axial spondyloarthritis

Pseudoerosions of Hands and Feet in Rheumatoid Arthritis: Anatomic Concepts and Redefinition

Contact Info

Product

Resources

About