Suspected allergic contact dermatitis to iodopropynyl butylcarbamate in an alcohol hand rub commonly used in Australian health-care settings

Toholka, Ryan; Nixon, Rosemary

doi:10.1111/ajd.12109

Cited by 7 publications

(10 citation statements)

References 12 publications

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“…True allergic reactions to alcohol‐based formulations are uncommon 28 . A HCW developed suspected ACD to iodopropynyl butylcarbamate, found in a common brand of ABHRs 31 . Cases of ACD to isopropanol have been reported 32–38 .…”

Section: Skin Reactions Related To Hand Hygiene and Glovesmentioning

confidence: 99%

‘Occupational dermatoses from Personal Protective Equipment during the COVID‐19 pandemic in the tropics – A Review’

Lee

Goh

2020

Acad Dermatol Venereol

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The COVID‐19 pandemic has enveloped the world and there has been a high incidence of occupational dermatoses related to Personal Protective Equipment (PPE) amongst healthcare workers (HCWs) during this period. Prevention and management of these conditions will not only improve staff morale and quality of life, but will also minimize the risk of breaching PPE protocol due to such symptoms. The tropical climate in Singapore predisposes HCWs to more skin damage and pruritus due to intense heat, high humidity and sun exposure. The effects of friction, occlusion, hyperhidrosis and overheating on the skin in the tropics should not be neglected. Preventive measures can be taken based on our recommendations, and the working environment can be made more conducive for frontline HCWs. We review the literature and discuss various preventive and management strategies for these occupational skin diseases for our frontline HCWs, especially those working in less controlled working environments beyond the hospital in Singapore. Shorter shifts and frequent breaks from PPE are recommended. Duration of continuous PPE‐usage should not exceed 6 h, with breaks in non‐contaminated areas every 2–3 h to hydrate and mitigate the risk of skin reactions. Other strategies, such as teledermatology, should be considered so that consultations can remain accessible, while ensuring the safety and well‐being of our clinical staff.

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Section: Skin Reactions Related To Hand Hygiene and Glovesmentioning

confidence: 99%

‘Occupational dermatoses from Personal Protective Equipment during the COVID‐19 pandemic in the tropics – A Review’

Lee

Goh

2020

Acad Dermatol Venereol

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“…41 In our study period there were only three relevant reactions; however, there was a positive prevalence rate of 0.7% in those tested, and an estimated positive prevalence of 0.5% in the total patch test population. In light of its occurrence in a commonly used hospital skin cleanser 42 we believe that this is currently an important allergen to monitor in a baseline series.…”

Section: Notable Inclusions To the Australian Baseline Seriesmentioning

confidence: 99%

The first Australian Baseline Series: Recommendations for patch testing in suspected contact dermatitis

et al. 2014

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“…2 Although it has traditionally been considered to have low allergenic potential, in the last 20 years an increasing number of cases of allergic contact dermatitis have been reported. [3][4][5][6] METHODS For a period of 7 years (2011)(2012)(2013)(2014)(2015)(2016)(2017) at the Dermatology Department of the University Hospital of Coimbra, IPBC 0.2% pet. (Chemotechnique Diagnostics, Vellinge, Sweden) was added to the baseline series and patch tested, often in association with other series and patients' own products.…”

mentioning

confidence: 99%

“…2 Although it has traditionally been considered to have low allergenic potential, in the last 20 years an increasing number of cases of allergic contact dermatitis have been reported. [3][4][5][6] (Table 1). No case of exclusive facial dermatitis was reported, but leg dermatitis with leg ulcer or chronic venous insufficiency and high exposure to topical drugs, emollients and medical devices with incomplete labelling was overrepresented (33.3% vs 6.5% in the whole population tested).…”

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confidence: 99%

Patch test reactivity to iodopropynyl butylcarbamate in consecutive patients during a period of 7 years

2019

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DISCUSSIONThis relatively low reactivity to IPBC, and the higher prevalence in males and those aged >40 years, are consistent with results from another European centre, 7 but are distinct from results from the last 10 years in North America. They showed higher reactivity to IPBC (between 3.1% and 4.7%), possibly because of the inclusion of doubtful results and the higher patch test concentration (0.5% pet). 8 Low IPBC reactivity contrasts with high reactivity to isothiazolinones (>14%), 9 which is still found among our patients in many household and professional products and occasional

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Suspected allergic contact dermatitis to iodopropynyl butylcarbamate in an alcohol hand rub commonly used in Australian health-care settings

Abstract: We report a case of suspected allergic contact dermatitis to the preservative and uncommon allergen iodopropynyl butylcarbamate, found in Microshield Angel hand gel, a skin cleanser commonly used in Australian health-care settings.

Cited by 7 publications

References 12 publications

‘Occupational dermatoses from Personal Protective Equipment during the COVID‐19 pandemic in the tropics – A Review’

‘Occupational dermatoses from Personal Protective Equipment during the COVID‐19 pandemic in the tropics – A Review’

The first Australian Baseline Series: Recommendations for patch testing in suspected contact dermatitis

Patch test reactivity to iodopropynyl butylcarbamate in consecutive patients during a period of 7 years

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