Suspected laryngeal granuloma secondary to chronic endotracheal intubation in a dog

Neilson, David M; Pinelas, Rui

doi:10.1111/vaa.12352

Cited by 2 publications

(1 citation statement)

References 3 publications

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“…Neoplasms involving the larynx in dogs have been described infrequently and include squamous cell carcinoma (Nazifi et al 2006), extramedullary plasmacytoma (Witham et al 2012), mast cell tumour (Beaumont et al 1979), rhabdomyosarcoma (Sanspoux 2016), chondrosarcoma (Shoieb 2014), melanoma and myxochondroma (Ramírez et al 2015). In contrast, non-neoplastic lesions are poorly characterised with inflammatory laryngeal diseases mentioned in a textbook (MacPhail 2017) and reports on granulomas (granulation tissue) associated with chronic intubation (Neilson & Pinelas 2016), brachycephalic obstructive airway syndrome (Sarran et al 2018) and secondary to Leishmania (Torrent et al 2018).…”

Section: Introductionmentioning

confidence: 99%

Infiltrative laryngeal disease in dogs

Dixon

Tivers²,

Packham

et al. 2020

J of Small Animal Practice

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Objectives To describe the clinical features and outcome of neoplastic and inflammatory infiltrative laryngeal disease in dogs. Materials and Methods Medical records at a single referral centre were retrospectively reviewed for dogs diagnosed with infiltrative laryngeal disease by CT or laryngoscopy. Results Fifteen dogs were included, with a median age of 6 years (range 1‐14 years). Thirteen dogs were diagnosed with inflammatory disease including granulation tissue (n = 4) and neutrophilic (n = 2), septic neutrophilic (n = 2), eosinophilic (n = 1) lymphocytic/plasmacytic (n = 1) and mixed/unclassified (n = 3) inflammation. One dog was diagnosed with large cell lymphoma and one dog was diagnosed with mast cell tumour. Twelve dogs survived to discharge. Follow‐up was available for 10 dogs diagnosed with inflammatory disease. Four had fully recovered (7, 10, 23 and 32 months) and one dog developed acute leukaemia and was euthanased at 2 months. Five dogs had recurrence of clinical signs at 1, 1, 5, 17 and 26 months. The dog with lymphoma was euthanased at 8 months and the dog with mast cell tumour died at 5 months. Clinical Significance In this cohort, infiltrative inflammatory lesions of the larynx were more common than neoplastic infiltration. For dogs that survived to discharge, outcome was fair although relapse was common.

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Section: Introductionmentioning

confidence: 99%

Infiltrative laryngeal disease in dogs

Dixon

Tivers²,

Packham

et al. 2020

J of Small Animal Practice

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Vocal fold granulomas in six brachycephalic dogs: clinical, macroscopical and histological features

Sarran¹,

Caron²,

Billet³

2018

J of Small Animal Practice

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Vocal cord granulomas are rarely observed in brachycephalic breeds but often reported in humans as contact granulomas. Six French bulldogs were included in this retrospective descriptive study. Endoscopic laryngeal examinations were performed on all dogs under general anaesthesia. Vocal cord lesions were exclusively unilateral, exophytic, approximately 3-mm wide ulcerated mucosal nodules, arising from the vocal cord. Histopathological examination mainly revealed chronic inflammatory changes on the laryngeal epithelium which were consistent with laryngeal granulomas described in humans, except for the location: vocal cord in dogs versus vocal process in humans. In humans, granulomas result from chronic physical or chemical insult to laryngeal mucosa (chronic cough or throat clearing, vocal abuse, gastro-esophageal reflux). In brachycephalic breeds, chronic inspiratory efforts and air turbulences and gastro-esophageal reflux are suspected to result in chronic laryngeal inflammation.

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Suspected laryngeal granuloma secondary to chronic endotracheal intubation in a dog

Cited by 2 publications

References 3 publications

Infiltrative laryngeal disease in dogs

Infiltrative laryngeal disease in dogs

Vocal fold granulomas in six brachycephalic dogs: clinical, macroscopical and histological features

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