Sustainable Effect of Ayurvedic Formulations in the Treatment of Nutritional Anemia in Adolescent Students

Prakash, Vaidya Balendu; Prakash, Shyam; Sharma, Rajesh; Pal, S.

doi:10.1089/acm.2008.0573

Cited by 10 publications

(9 citation statements)

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“…These drugs increase the agni (metabolic process) and which in turn help in correcting the deficits in the metabolism. Another study[33] has also shown the therapeutic effect and sustainability effect of Ayurveda formulations in nutritional deficiency anaemia in children.…”

Section: Discussionmentioning

confidence: 99%

Effect of Ayurveda Medications (Kasīsa Bhasma and Dhātrī Avaleha) on Iron Deficiency Anaemia: A Randomized Controlled Study

et al. 2016

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Background:This paper explores the role that Ayurveda can play in the management of Iron Deficiency Anaemia, a major nutritional deficiency disorder affecting people across the globe.Methodology:Forty (40) patients suffering from Iron deficiency anaemia as per WHO guidelines, between the age group of 20 to 60 yrs of either sex participated in the study. Study was a randomized, controlled, open label clinical study. Patients were randomly divided into two groups: Group D (n = 20) received Dhārī avaleha 10 g twice a day after food. Group K (n = 20) received capsules Kasīsa bhasma 125 mg thrice a day. Both interventions were administered for 30 days and the subjects were followed up for next 30 days with placebo capsules to assess the sustainability of the effects. Assessments were done at baseline, 30th and 60th days. Primary outcome measure was hemoglobin estimation (Hb) and secondary outcome measures were the other hematological parameters such as Red blood cell (RBC) indices, total RBC count, Packed Cell volume (PCV) and Peripheral Blood smear study.Results:Both interventions produced significant improvements (P < 0.001). Kasīsa bhasma was better compared to dhātrī avaleha in terms of primary (P < 0.0001) and secondary outcomes. Comparison of outcomes from base line – 30th day, base line – 60th day and 30th – 60th day showed significant (P < 0.0001) improvement in both the groups in parameters such as haemoglobin, MCV and MCH. Hence improvements sustained during placebo intervened sustainability period also.Conclusions:Study effectively shows that Kasīsa bhasma is better then Dhātrī avaleha. Improvements by both interventions were sustained even during the sustainability period.

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Section: Discussionmentioning

confidence: 99%

Effect of Ayurveda Medications (Kasīsa Bhasma and Dhātrī Avaleha) on Iron Deficiency Anaemia: A Randomized Controlled Study

et al. 2016

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“…Los terapéuticos empleados para tratar la anemia incluyeron formulaciones tradicionales japonesa, china y ayurvédica; la Espirulina (alga filamentosa); una dieta rica en hígado y músculo, y el extracto de lechuga. El número de sujetos incluidos en el estudio varió de 1 a 1646 participantes, con respecto al sexo, dos estudios se realizaron sobre población femenina (Akase et al (19) y Baumslag et al (20) ), tres en participantes de ambos sexos (Prakash et al (21) , Selmi et al (18) y Afolabi et al (17) ), mientras que el estudio experimental y el de serie de casos no indicaron el sexo de los participantes.…”

Section: Características De Los Estudiosunclassified

“…Solo en el caso del estudio Afolabi et al (17) , el diseño y estrategia del estudio fue diferente al resto de los estudios, pues la unidad de análisis fue la célula sanguínea falciforme humana. Los ECA y el estudio experimental consideraron como controles del estudio fármacos como la ferromia (Akase et al (17) y el almidón (Prakash et al (21) ). Los estudios cuasiexperimentales, el reporte y la serie de casos, emplearon como controles el perfil de diagnóstico y características de línea base sobre el mismo grupo de estudio.…”

Section: Características De Los Estudiosunclassified

“…El estudio de Akase et al (17) no precisa si se trata, o no, de un doble ciego; por otro lado, no se describe el método de aleatorización de los participantes, en tanto que el trabajo de Prakash et al (21) no indica cuántos retiros y abandonos se reportaron a lo largo del estudio. El estudio fue descrito como un ciego simple (o único); sin embargo, el método de cegamiento no fue el más apropiado.…”

Section: Evaluación De Riesgo De Sesgounclassified

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Eficacia de la trofoterapia en el tratamiento de la anemia: estudio bibliométrico

Reyes-Mandujano¹,

Rosa²,

Trujillo-Villarroel³

2016

Rev. per. med. integr.

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Objetivo. Identificar, evaluar y sistematizar información acerca de la eficacia de la trofoterapia en el manejo de la anemia. Materiales y métodos. Se realizó una búsqueda entre mayo y junio de 2014, en las bases de datos: PUBMED, EBSCO, Science Direct, Scopus, y EMBASE. Para la selección de los artículos se consultó la Cochrane Handbook of Systematic Reviews of Intervention, versión 5.1.0. Se utilizó el formulario de extracción de datos Cochrane (2007) modificado, para obtener la información de los artículos según los criterios de inclusión. Para evaluar la calidad metodológica de la evidencia se empleó la "escala de Jadad", en el caso de los ensayos clínicos aleatorizados, y una lista de calidad estándar para estudios primarios de diferentes campos, descritos. Resultados. Seis artículos cumplieron con los criterios de inclusión, solo dos de ellos tuvieron una adecuada calidad metodológica. Dos estudios referían el uso de preparados tradicionales en el tratamiento de la anemia; dos estudios consideraron alimentos para el tratamiento de la anemia y un estudio analizó extractos metanólicos. Los términos "trofoterapia" o trophotherapy no fueron encontrados en los tesauros (DeCS y MeSH) y ningún artículo científico hizo referencia al término trophotherapy en el título. Conclusiones. Es importante definir y armonizar los conceptos en trofoterapia, para que estas puedan ser estudiadas, validadas e incorporadas en el sistema convencional de salud; sin embargo, existen indicios de la eficacia de Solenostemon monostachyus, Ipomoea involucrata, el aceite de semilla de Carica papaya y del alga espirulina para el tratamiento de la anemia falciforme y nutricional, pero estas investigaciones no se han abordado en el marco de la filosofía y paradigmas de la trofoterapia. (2007) was used to obtain information on the items according to the inclusion criteria. The "Jadad Scale" was used to assess the methodological quality of the evidence in the randomized clinical trials; and a list of standard quality to assess primary studies of different fields. Results: Six (06) articles met the inclusion criteria; only two (02) of them had adequate methodological quality. Two (02) studies have shown the use of traditional preparations in the treatment of anemia; two (02) studies have shown the use of food for the treatment of anemia and (01) study have analyzed methanolic extracts. The terms "trofoterapia" or "trophoterapy" haven't found in the thesaurus (DeCS and MeSH). We haven't found any scientific article with the term " trophoterapy " in the title. Conclusions: The definition and standardization of the concepts in trofoterapia is important. Only after that is possible its study, validation and incorporation in the conventional health system. However, we've found evidence of the effectiveness of Solenostemon monostachyus, Ipomoea involucrata, Carica papaya oil seed and spirulina seaweed for the treatment of sickle cell and nutritional anemia; but these investigations haven't included the philosophy and paradigms of trophotherapy.

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“…One of the reasons for this may be the fact that Rasa Shastra is well tested science; hence, there was no need of fresh proof. However, few properly conducted clinical studies indicated that nutritional anemia in nonpregnant adolescent girls can be improved by a daily dose of Sootshekhar Rasa (250 mg) plus Sitopaladi Churna (400 mg) [11]. Another clinical study of Kukkutanda twak bhasma reveals statistically significant improvement in Swetapradara, an important gynecological disorder [12].…”

Section: Therapeutic Use Of Bhasmasmentioning

confidence: 99%

The Ayurvedic Bhasma: The Ancient Science of Nanomedicine

Pal

2015

PNM

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Nanomedicine is the relevance of nanotechnology in the area of healthcare, diagnosis of disease, cure and prevention of disease. Nanotechnology covers the diverse area of matters at dimensions between approximately 1 to 100 nanometers. Nanotechnology has enormous applications in drug delivery field. Nano drug delivery systems can reduce the drug consumption and side-effects by lowering the deposition of the active agent in the non targeted sites. Ayurveda is thousands of years old holistic system of Indian medicine. Various herbs, metals and non-metals preparations are used as medicine in Ayurveda. In the Ayurvedic description, several metallic preparations called Bhasma are in clinical use since 8th century AD. The Puta system of Ayurveda describes that metals or minerals should be heated at high temperature for melting and then it quench in suitable media like herbal juices or decoction for specified times. The Bhasma (incinerated metals) is obtained by repeating these methods several times. In this process the toxic effects of the metals are not only nullified but are transformed into biologically active nanoparticles. When various Bhasmas viz. Swarna bhasma, Makshika bhasma, Abhrak bhasma, Tamra bhasma and Louha bhasma were subjected to analysis under electron microscope it was found that they were similar to nanocrystalline materials possessing similar physico-chemical properties. The therapeutic effect of Bhasma may be attributed to large surface area of materials and small particle size by which they can easily transported into cell nucleus and to specific target sites as desired.

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Sustainable Effect of Ayurvedic Formulations in the Treatment of Nutritional Anemia in Adolescent Students

Abstract: We conclude that a daily dose of Sootshekhar Rasa (250 mg) plus Sitopaladi Churna (400 mg) can produce sustainable improvement of nutritional anemia in adolescent students.

Cited by 10 publications

References 19 publications

Effect of Ayurveda Medications (Kasīsa Bhasma and Dhātrī Avaleha) on Iron Deficiency Anaemia: A Randomized Controlled Study

Effect of Ayurveda Medications (Kasīsa Bhasma and Dhātrī Avaleha) on Iron Deficiency Anaemia: A Randomized Controlled Study

Eficacia de la trofoterapia en el tratamiento de la anemia: estudio bibliométrico

The Ayurvedic Bhasma: The Ancient Science of Nanomedicine

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