Sustainable Laboratory Capacity Building After the 2014 Ebola Outbreak in the Republic of Guinea

IntroductionLearning is a key attribute of a resilient health system and, therefore, is central to health system strengthening. The main objective of this study was to analyse how Guinea’s health system has learnt from the response to outbreaks between 2014 and 2021.MethodsWe used a retrospective longitudinal single embedded case study design, applying the framework conceptualised by Sheikh and Abimbola for analysing learning health systems. Data were collected employing a mixed methods systematic review carried out in March 2022 and an online survey conducted in April 2022.ResultsThe 70 reports included in the evidence synthesis were about the 2014–2016 Ebola virus disease (EVD), Measles, Lassa Fever, COVID-19, 2021 EVD and Marburg virus disease. The main lessons were from 2014 to 2016 EVD and included: early community engagement in the response, social mobilisation, prioritising investment in health personnel, early involvement of anthropologists, developing health infrastructure and equipment and ensuring crisis communication. They were learnt through information (research and experts’ opinions), action/practice and double-loop and were progressively incorporated in the response to future outbreaks through deliberation, single-loop, double-loop and triple-loop learning. However, advanced learning aspects (learning through action, double-loop and triple-loop) were limited within the health system. Nevertheless, the health system successfully controlled COVID-19, the 2021 EVD and Marburg virus disease. Survey respondents’ commonly reported that enablers were the creation of the national agency for health security and support from development partners. Barriers included cultural and political issues and lack of funding. Common recommendations included establishing a knowledge management unit within the Ministry of Health with representatives at regional and district levels, investing in human capacities and improving the governance and management system.ConclusionOur study highlights the importance of learning. The health system performed well and achieved encouraging and better outbreak response outcomes over time with learning that occurred.

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“…Built health infrastructures (38 epidemic treatment centres and laboratory capacity were built) 85 172…”

Section: Resultsmentioning

confidence: 99%

How has Guinea learnt from the response to outbreaks? A learning health system analysis

et al. 2023

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“…For instance, the CDC's Surveillance Training for Ebola Preparedness (STEP) initiative was shown to be a successful mentorship and competence-based initiative that collaborated with various local training institutes and organizations to rapidly build the surveillance capacity of district surveillance officers in Mali, Guinea-Bissau, Senegal and Ivory Coast during the Ebola outbreak in West Africa ( 40 ). Along with the STEP initiative, implementation of laboratory capacity building programs to strengthen bio-risk and quality management systems, diagnostics and facility engineering, and bio-surveillance capacity was able to bolster emergency preparedness and response ( 41 ). Perhaps most notably, infection prevention and control capacity building programs for HCWs registered positive benefits on knowledge and practices of HCWs in the fight against Ebola outbreak in DRC ( 42 ) and Western Africa ( 43 ).…”

Section: Ebola Outbreak In West-africamentioning

confidence: 99%

Pacing Forward in the Face of Fragility: Lessons From African Institutions and Governments' Response to Public Health Emergencies

Bitanihirwe

Ssewanyana

Ddumba-Nyanzi³

2021

Front. Public Health

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Africa is home to 54 United Nation member states, each possessing a wealth of ethno-cultural, physiographic, and economic diversity. While Africa is credited as having the youngest population in the world, it also exhibits a unique set of “unfortunate realties” ranging from famine and poverty to volatile politics, conflicts, and diseases. These unfortunate realities all converge around social inequalities in health, that are compounded by fragile healthcare systems and a lack of political will by the continent's leaders to improve smart investment and infrastructure planning for the benefit of its people. Noteworthy are the disparities in responsive approaches to crises and emergencies that exist across African governments and institutions. In this context, the present article draws attention to 3 distinct public health emergencies (PHEs) that have occurred in Africa since 2010. We focus on the 2013–2016 Ebola outbreak in Western Africa, the ongoing COVID-19 pandemic which continues to spread throughout the continent, and the destructive locust swarms that ravaged crops across East Africa in 2020. Our aim is to provide an integrated perspective on how governments and institutions handled these PHEs and how scientific and technological innovation, along with educational response played a role in the decision-making process. We conclude by touching on public health policies and strategies to address the development of sustainable health care systems with the potential to improve the health and well-being of the African people.

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“…Located on the west coast of Africa, Sierra Leone, being one of the most undeveloped countries in the world, has a particularly vulnerable public health system ( 4 , 5 ). Even though Sierra Leone reacted quickly to the threat of COVID-19, implementing policies to contain the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ( 6 ), COVID-19 emerged as a serious public health challenge due to the weak health system, poverty, cultural norms, and limited medical resources ( 7 , 8 ) [e.g., a single ventilator was available for the whole population of Sierra Leone in the initial stage of the COVID-19 pandemic ( 1 )], which led to significant health concerns and socioeconomic issues.…”

Section: Introductionmentioning

confidence: 99%

Epidemiological Trends of Coronavirus Disease 2019 in Sierra Leone From March 2020 to October 2021

Liu

Gao²,

Xue³

et al. 2022

Front. Public Health

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Coronavirus disease 2019 (COVID-19), a serious public health challenge the world over, has led to significant health concerns in Sierra Leone. In the present study, epidemic indices, such as the number of cases, positivity rate, reproduction rate (R0), case fatality rate (CFR), age, and sex, were used to characterize the epidemiological trends of COVID-19. As of October 31, 2021, a total of 6,398 cases and 121 related deaths had been confirmed. The total number of COVID-19 reverse transcription polymerase chain reaction (RT-PCR) tests conducted to October 31, 2021, was 249,534, and the average positivity rate was 2.56%. Three waves of COVID-19 were recorded, occurring during weeks 15–46 in 2020 (2,369 cases), week 47 in 2020 to week 16 in 2021 (1,665 cases), and weeks 17–43 in 2021 (2,364 cases), respectively. Remarkably, there was no increase in the numbers of confirmed COVID-19 cases despite rising test numbers throughout the three waves. Moreover, three high R0 values were observed before each wave. The number of positive cases significantly correlated with positive numbers of international arrivals (P < 0.01), deaths (P < 0.01), and the positivity rate of tested samples (P < 0.01). Moreover, all of the deaths occurred during the peak of the three waves. Our results indicate that there was a low level of COVID-19 epidemic in Sierra Leone and that COVID-19's introduction led to local transmission. It is vital to fight against the spread of SARS-CoV-2 from the source of origin by strengthening testing and management of people entering the country. Our findings will provide important clues for expanding sample screening and will contribute to the reasonable allocation of medical resources.

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Sustainable Laboratory Capacity Building After the 2014 Ebola Outbreak in the Republic of Guinea

Cited by 3 publications

References 13 publications

How has Guinea learnt from the response to outbreaks? A learning health system analysis

How has Guinea learnt from the response to outbreaks? A learning health system analysis

Pacing Forward in the Face of Fragility: Lessons From African Institutions and Governments' Response to Public Health Emergencies

Epidemiological Trends of Coronavirus Disease 2019 in Sierra Leone From March 2020 to October 2021

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