In Japan, expressway bridges are aging and deteriorating because of increases in traffic volume and loading, harsh environments and other factors. Therefore, a renewal plan for bridges was drafted to address this issue in 2015. The main works include replacing reinforced concrete (RC) slabs of steel girder bridges with precast prestressed concrete (PC) slabs. In renewal plan for RC slab, if the severe deterioration occurs in the RC slab, that will be renewed to high durability precast PC slab. In the design of the new PC slab, the structure and material is determined in consideration of the degradation factors of the old RC slab. The new PC slab is necessary to have sufficient durability against the environmental action during design service life and to have sufficient safety against automobile load. In this paper, the design method and structure of the new PC slab are described.