“…A key feature of this compound is its use as a solvent, reported for the first time in 2014 by Sherwood et al Because of its bioavailability, lower toxicity, biodegradability, and high performance as a dipolar aprotic solvent, it has already entered the marketplace and is expected to replace conventional N -methyl-2-pyrrolidone (NMP) and N , N -dimethylformamide (DMF), which will be restricted by Registration, Evaluation, Authorization, and Restriction of Chemicals (REACH) for industrial use. Cyrene is also used as a synthetic raw material and for extracting valuable bioactive compounds, such as hesperidin and rutin . Deeper hydrogenation converts LGO into levoglucosanol and then tetrahydrofurandimethanol (THFDM). , The hydrogenolysis products of THFDM, 1,2,6-hexanetriol and 1,6-hexanediol, are widely used in industry for polyester and polyurethane production.…”