Sustained Change in ADHD: Interventions and Variables That Lead to Durable Improvements in Symptoms and Quality of Life

García, Trinidad; Pérez, Celestino Rodríguez

doi:10.3390/su132413721

Cited by 2 publications

(2 citation statements)

References 25 publications

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“…The main types of ADHD include being inattentive, hyperactive/impulsive, or showing a combined type of presentation. ADHD can affect many aspects of social life, including family, friends, school, and work relationships [9]. The symptoms of ADHD are very complex and involve problems with learning, inattention, and hyperactivity or impulsivity.…”

Section: Introductionmentioning

confidence: 99%

Alterations in the Glycan Composition of Serum Glycoproteins in Attention-Deficit Hyperactivity Disorder

Kianičková,

Pažitná,

Kundalia

et al. 2023

IJMS

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Changes in protein glycosylation are associated with most biological processes, and the importance of glycomic analysis in the research of disorders is constantly increasing, including in the neurodevelopmental field. We glycoprofiled sera in 10 children with attention-deficit hyperactivity disorder (ADHD) and 10 matching healthy controls for 3 types of samples: whole serum, sera after depletion of abundant proteins (albumin and IgG), and isolated IgG. The analytical methods used were a lectin-based glycoprotein microarray enabling high-throughput glycan analysis and matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry (MS) as a standard method for the identification of glycan structures. For microarray analysis, the samples printed on microarray slides were incubated with biotinylated lectins and detected using the fluorescent conjugate of streptavidin by a microarray scanner. In the ADHD patient samples, we found increased antennary fucosylation, decreased di-/triantennary N-glycans with bisecting N-acetylglucosamine (GlcNAc), and decreased α2-3 sialylation. The results obtained by both independent methods were consistent. The study’s sample size and design do not allow far-reaching conclusions to be drawn. In any case, there is a strong demand for a better and more comprehensive diagnosis of ADHD, and the obtained results emphasize that the presented approach brings new horizons to studying functional associations of glycan alterations in ADHD.

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Section: Introductionmentioning

confidence: 99%

Alterations in the Glycan Composition of Serum Glycoproteins in Attention-Deficit Hyperactivity Disorder

Kianičková,

Pažitná,

Kundalia

et al. 2023

IJMS

View full text Add to dashboard Cite

show abstract

“…Attention deficit hyperactivity disorder (ADHD) is one of the most commonly diagnosed neuropediatric disorders (Faraone et al, 2021;Onandia-Hinchado et al, 2021). The essential feature of ADHD is a persistent pattern of impaired attention and executive functioning, which interferes with development and causes impairment in multiple settings such as home, school or work (Colomer et al, 2017;García & Rodríguez, 2021;Onandia-Hinchado et al, 2021).…”

mentioning

confidence: 99%

State of the art and new directions of Quantitative Electroencephalography use in Differential Diagnosis of ADHD

Chiarenza¹,

Pérez-Elvira²

2022

RPCNA

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Advances in technology in recent years have made the use of quantitative electroencephalogram more accessible to clinicians. The incorporation of normative databases in QEEG studies and the possibility of detecting different electroencephalographic patterns in patients with a given pathology, despite showing an apparent symptomatology homogeneity, make it an interesting source of information. The relationship of these patterns with a possible response to treatment or with prognostic estimates would justify its inclusion as a routine test in the process of the differential diagnosis of ADHD. In this paper, we present the possible benefits of the use of QEEG in the differential diagnosis of ADHD, the different electroencephalographic patterns associated with ADHD most common in the literature, and a case showcasing the use of the technique in a patient with ADHD

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Sustained Change in ADHD: Interventions and Variables That Lead to Durable Improvements in Symptoms and Quality of Life

Abstract: Attention Deficit/Hyperactivity Disorder (ADHD) is one of the most common conditions in childhood, but it also persists into adolescence and adulthood, showing prevalence rates from 5 [...]

Cited by 2 publications

References 25 publications

Alterations in the Glycan Composition of Serum Glycoproteins in Attention-Deficit Hyperactivity Disorder

Alterations in the Glycan Composition of Serum Glycoproteins in Attention-Deficit Hyperactivity Disorder

State of the art and new directions of Quantitative Electroencephalography use in Differential Diagnosis of ADHD

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