Sustained effect of couples' HIV counselling and testing on risk reduction among Zambian HIV serodiscordant couples

Wall, Kristin M.; Kilembe, William; Vwalika, Bellington; Haddad, Lisa; Lakhi, Shabir; Onwubiko, Udodirim; Khu, Naw Htee; Brill, Ilene; Chavuma, Roy; Vwalika, Cheswa; Mwananyanda, Lawrence; Chomba, Elwyn; Mulenga, Joseph; Tichacek, Amanda; Allen, Susan

doi:10.1136/sextrans-2016-052743

Cited by 44 publications

(34 citation statements)

References 24 publications

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“…CHTC entails simultaneous HIV testing for partners and facilitated mutual disclosure. Previous research has found that CHTC promotes sexual risk reduction, especially among serodiscordant partnerships [11][12][13] . However, despite its benefits, uptake of CHTC has remained low across multiple contexts in Sub-Saharan Africa (SSA) and specifically in South Africa.…”

Section: Resultsmentioning

confidence: 96%

Results of a Couples-Based Randomized Controlled Trial Aimed to Increase Testing for HIV

Darbes

McGrath

Hosegood

et al. 2019

JAIDS Journal of Acquired Immune Deficiency Syndromes

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Background Although couples-based HIV testing and counseling (CHTC) is effective for facilitating mutual disclosure and linkage to HIV care, uptake remains low. Using a randomized controlled design, we tested the efficacy of a behavioral couples-based intervention aimed to increase CHTC. Setting: The Vulindlela district of KwaZulu-Natal, South Africa. Methods Couples were recruited from the community (e.g., markets, community events). Couples were excluded if mutual HIV serostatus disclosure had occurred. Both partners had to report being each other's primary partner and relationship length was at least six months. Assessments occurred at baseline, and 3-, 6-, and 9-months post-intervention. Eligible couples attended a group session (3-4 hours) after which randomization occurred. Intervention

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Section: Resultsmentioning

confidence: 96%

Results of a Couples-Based Randomized Controlled Trial Aimed to Increase Testing for HIV

Darbes

McGrath

Hosegood

et al. 2019

JAIDS Journal of Acquired Immune Deficiency Syndromes

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“…were taken, in which the frequency of unprotected sex was reduced. A study in Zambia showed that timely intervention following diagnosis of index might be resulted in a significant decreased frequency of unprotected sexual intercourse between serodiscordant couples, as well as a significant drop in the HIV seroconversion rate [ 19 ]. Our current study showed that following diagnosis of the index case, the HIV seroconversion rate among HIV-negative partners was 1/23 of pre-diagnosis as a result of various intervention measures, which was similar to results obtained from previous research [ 23 ].…”

Section: Discussionmentioning

confidence: 99%

HIV transmission between spouses living in Lu'an city, Anhui province, China: a longitudinal study

Ma¹,

Chen²,

Jin³

et al. 2019

Epidemiol. Infect.

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This study aims to investigate the human immunodeficiency virus (HIV) transmission rate in HIV serodiscordant couples, in addition to the relevant influencing factors. From January 1999 to August 2016, patients with HIV/AIDS (index cases) along with their fixed partners were registered and monitored to determine the rate of HIV transmission between couples, as well as relevant influencing factors. A total of 231 HIV-positive couples were investigated, of these, 45-negative (19.48%) partners were infected with HIV via sexual transmission prior to diagnosis of the first case detected in couples. After diagnosis, the transmission rate between spouses was 0.39 per 100 person-years (2/507.7), and the cumulative transmission rate was 1.08% (2/186), which was significantly lower than the transmission rate before diagnosis (χ2 = 35.714, P < 0.001). Among the 119 HIV/AIDS patients who received antiretroviral therapy (ART), the transmission rate was 0 (0/119), whereas the transmission rate was 2.99% (2/67) in HIV/AIDS patients who did not receive ART. In addition, HIV transmission rate in serodiscordant couples was high prior to diagnosis of the index case. However, following diagnosis, the transmission rate was reduced, and the risk of transmission in the index case with antiviral treatment was null. Therefore, a prompt intervention in HIV discordant couples with ART of index case is vital to reduce the risk of HIV transmission.

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“…Couple-based HIV counseling and testing could be considered as the appropriate intervention, providing the opportunity to discuss the sexual agreement under guidance of experienced counselors. This has been proven to be effective in the potential decrease of HIV incidence among heterosexual couples in Africa [ 51 , 52 ], and it has also proven to be acceptable and safe among MSM in America [ 21 , 23 ]. Since few studies in China have focused on this aspect of HIV prevention and because there is an apparent lack of awareness existing among MSM, the development of interventions to promote open communication skills among MSM couples, such as couple-based HIV testing and counseling, is needed in China.…”

Section: Discussionmentioning

confidence: 99%

Intimate relationship characteristics as determinants of HIV risk among men who have sex with regular male sex partners: a cross-sectional study in Guangzhou, China

He¹,

Xu²,

Cheng³

et al. 2018

BMC Infect Dis

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BackgroundChina faces a serious HIV epidemic among men who have sex with men (MSM), and a large proportion of new infections are attributed to their regular male sex partners (RP). The objective of this study was to investigate the association between intimate relationship characteristics and HIV-related behaviors among MSM with RP in Guangzhou, China.MethodsA convenience-sampling method was used in data collection. A total of 608 MSM were screened, of whom 406 HIV negative MSM with at least one RP in the past six months were used for data analysis. Three-step logistic regressions were used to analyze the data.ResultsThe prevalence of unprotected anal intercourse (UAI) with regular male sex partners, non-regular male sex partners, and concurrent UAI in the past six months was 53.9%, 23.6%, 20.7%, respectively. Variables associated with UAI with regular male sex partners included expectations for this relationship (adjusted odds ratio in multiple forward stepwise logistic regression, ORm = 1.66) and open communication about the sexual relationship (ORm = 1.79), while expectations for the relationship (ORm = 0.46 to 0.54) and conflicts of interest (ORm = 5.46 to 5.97) were associated with concurrent UAI and UAI with non-regular male sex partners.ConclusionIntimate relationship characteristics were related to HIV-related risk behaviors. Future HIV prevention interventions should take MSM couples into consideration, include a focus on the quality of their intimate relationships, and encourage open communication about their sexual relationships.Electronic supplementary materialThe online version of this article (10.1186/s12879-018-3044-6) contains supplementary material, which is available to authorized users.

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Sustained effect of couples' HIV counselling and testing on risk reduction among Zambian HIV serodiscordant couples

Cited by 44 publications

References 24 publications

Results of a Couples-Based Randomized Controlled Trial Aimed to Increase Testing for HIV

Results of a Couples-Based Randomized Controlled Trial Aimed to Increase Testing for HIV

HIV transmission between spouses living in Lu'an city, Anhui province, China: a longitudinal study

Intimate relationship characteristics as determinants of HIV risk among men who have sex with regular male sex partners: a cross-sectional study in Guangzhou, China

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