Sustained release tablet of theophylline by hot melt wax coating technology

Padsalgi, Amol; Bidkar, Sanjay; Jadhav, Vijay J.; Sheladiya, Deepak

doi:10.4103/0973-8398.41561

Cited by 5 publications

(5 citation statements)

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“…However, pouring techniques and in-situ hot melt coating are used more often in the context of research than in large-scale manufacturing. The use of pouring techniques in pan coating requires a high degree of attention and care, as poor execution may cause twinning as well as inferior coating homogeneity and efficiency ( 52 ). In-situ hot melt coating can be used without any additional hot-melt equipment ( e.g., nozzle, heating system etc.…”

Section: Selection Of Lipid-excipients and Melt Processing Techniquesmentioning

confidence: 99%

Solvent-Free Melting Techniques for the Preparation of Lipid-Based Solid Oral Formulations

2015

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Lipid excipients are applied for numerous purposes such as taste masking, controlled release, improvement of swallowability and moisture protection. Several melting techniques have evolved in the last decades. Common examples are melt coating, melt granulation and melt extrusion. The required equipment ranges from ordinary glass beakers for lab scale up to large machines such as fluid bed coaters, spray dryers or extruders. This allows for upscaling to pilot or production scale. Solvent free melt processing provides a cost-effective, time-saving and eco-friendly method for the food and pharmaceutical industries. This review intends to give a critical overview of the published literature on experiences, formulations and challenges and to show possibilities for future developments in this promising field. Moreover, it should serve as a guide for selecting the best excipients and manufacturing techniques for the development of a product with specific properties using solvent free melt processing.

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Section: Selection Of Lipid-excipients and Melt Processing Techniquesmentioning

confidence: 99%

Solvent-Free Melting Techniques for the Preparation of Lipid-Based Solid Oral Formulations

2015

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“…For sustain release applications, coating excipients of special interest can be divided broadly as natural and synthetic waxes, hydrogenated vegetable waxes, polyglycolysed glycerides. Examples of some marketed hot melt coating excipients are Gelucires, Precirol, Stearines, Myvaplex, Compritol 888ATO [11][12][13][14]. The various technologies of hot melt coatings are:…”

Section: Hot Melt Coatingmentioning

confidence: 99%

Solventless coating for Tablets: An alternative to conventional coating technique

Jaimini¹,

Jain²,

Sharma³

et al. 2014

IJPBR

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There are many ways to coat tablets. Coatings are a very important part in the formulation of pharmaceutical dosage form to achieve excellent formulation quality (e.g., color, texture, mouth feel, and taste masking), physical and chemical protection for the drugs in the dosage forms, and modification of drug release characteristics. Most film coatings are applied as aqueous or organic-based polymer solutions. Such film coating brings their own disadvantages. Solventless coatings are alternative technique of coating. Solventless coating technologies can overcome many of the disadvantages associated with the use of solvents (e.g., solvent exposure, solvent disposal, and residual solvent in product) in pharmaceutical coating. Solventless processing reduces the overall cost by eliminating the tedious and expensive processes of solvent disposal/treatment. In addition, it can significantly reduce the processing time due to reduction of step of drying/evaporation. These environment-friendly processes are performed without any heat in most cases (except hot-melt coating) and thus can provide an alternative technology to coat temperature-sensitive drugs. This review includes various solventless coating methods like magnetic assisted impaction coating , hotmelt coating, supercritical fluid spray coating, electrostatic coating, dry powder coating, and photocurable coating that can be used to coat the pharmaceutical dosage forms.

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“…It offers several benefits and potential for a wide variety of application in pharmaceutical formulation [43][44][45][46] . The most common applications of this technique consist of the coating of pellets, granules and powder particles, particularly to obtain moisture-protected or modified-release dosage forms 47 .…”

Section: Hot Melt Coatingmentioning

confidence: 99%

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2012

IJPSR

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Sustained release tablet of theophylline by hot melt wax coating technology

Cited by 5 publications

References 0 publications

Solvent-Free Melting Techniques for the Preparation of Lipid-Based Solid Oral Formulations

Solvent-Free Melting Techniques for the Preparation of Lipid-Based Solid Oral Formulations

Solventless coating for Tablets: An alternative to conventional coating technique

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