Sustancias psicoactivas y embarazo. Estudio en una población hospitalaria de Uruguay

Magri, Raquel; Míguez, Hugo A; Hutson, Janine R.; Suárez, Héctor; Menéndez, Adriana; Parodi, Verónica; Koren, Gideon; Bustos, Raúl

doi:10.1016/s1575-0973(08)74551-3

Cited by 2 publications

(7 citation statements)

References 28 publications

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“…Nine studies on the prevalence of PAE, obtained via maternal self-reports and meconium testing (Hutson et al [37] and Magri et al [38,39] were published in iteration, and Derauf et al [40,41] are dual publications), were identified from the literature. Data on the prevalence of PAE, obtained via maternal self-reports and meconium testing, were available from only six countries: Canada [15,42], Germany [43], Italy [44,45], Spain [36,44,46], Uruguay [37-39], and the United States [40,41].…”

Section: Resultsmentioning

confidence: 99%

“…Data on the prevalence of PAE, obtained via maternal self-reports and meconium testing, were available from only six countries: Canada [15,42], Germany [43], Italy [44,45], Spain [36,44,46], Uruguay [37-39], and the United States [40,41]. …”

Section: Resultsmentioning

confidence: 99%

“…AUDIT: Alcohol Use Disorders Identification Test; FAEE: fatty acid ethyl esters; n/a: not available; SES: socio-economic status. a Levels of increased sensitivity may not total percentage figures obtained via meconium testing divided by percentage figures obtained via self-reports due to rounding errors. b Pichini et al [44] reported results for two study sites (Italy and Spain). c Reported “daily” consumption. d Hutson et al [37] and Magri et al [38,39] were published in iteration. e Derauf et al [40,41] are dual publication. f Excludes 5 women who reported alcohol use during the first trimester only.…”

Section: Resultsmentioning

confidence: 99%

“…Based on the self-reported data, the prevalence of PAE ranged from 0% (in Spain [36]) to 36.8% (in Uruguay [37-39]). In comparison, based on the meconium testing data, the prevalence of PAE ranged from 2.5% (in Canada [15]) to 45.0% (in Spain [46]; Table 1).…”

Section: Resultsmentioning

confidence: 99%

“…In comparison, based on the meconium testing data, the prevalence of PAE ranged from 2.5% (in Canada [15]) to 45.0% (in Spain [46]; Table 1). The prevalence of PAE, obtained via meconium testing, ranged from 1.2 times (in Uruguay [37-39]) to 43 times higher (in Germany [43]) than that obtained via maternal self-reports (Table 1 and Figure 2). …”

Section: Resultsmentioning

confidence: 99%

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A comparison of the prevalence of prenatal alcohol exposure obtained via maternal self-reports versus meconium testing: a systematic literature review and meta-analysis

Lange

Shield

Koren

et al. 2014

BMC Pregnancy Childbirth

130

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BackgroundMaternal self-reports, used for the detection of prenatal alcohol exposure (PAE), may lack validity, necessitating the use of an objective biomarker. The detection of fatty acid ethyl esters (products of non-oxidative ethanol metabolism) in meconium has been established as a novel biomarker of PAE. The purpose of the current study was to compare the prevalence of PAE as reported via maternal self-reports with the results of meconium testing, and to quantify the disparity between these two methods.MethodsA systematic literature search for studies reporting on the prevalence of PAE, using maternal self-reports in combination with meconium testing, was conducted using multiple electronic bibliographic databases. Pooled prevalence estimates and 95% confidence intervals (CI) were calculated based on eight studies, using the Mantel-Haenszel method, assuming a random effects model. A random effects meta-regression was performed to test for a difference.ResultsThe pooled prevalence of PAE as measured by meconium testing was 4.26 (95% CI: 1.34-13.57) times the pooled prevalence of PAE as measured by maternal self-reports. Large variations across the studies in regard to the difference between estimates obtained from maternal self-reports and those obtained from meconium testing were observed.ConclusionsIf maternal self-reports are the sole information source upon which health care professionals rely, a number of infants who were prenatally exposed to alcohol are not being recognized as such. However, further research is needed in order to validate existing biomarkers, as well as discover new biomarkers, for the detection of PAE.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 3 more Smart Citations

A comparison of the prevalence of prenatal alcohol exposure obtained via maternal self-reports versus meconium testing: a systematic literature review and meta-analysis

Lange

Shield

Koren

et al. 2014

BMC Pregnancy Childbirth

130

View full text Add to dashboard Cite

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Psychometric Properties of Brief Screening Tests for Alcohol Use Disorders during Pregnancy in Argentina

López

Lichtenberger

Conde

et al. 2017

Rev Bras Ginecol Obstet

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Background Considering the physical, mental and behavioral problems related to fetal alcohol exposure, prenatal clinical guides suggest a brief evaluation of alcohol consumption during pregnancy to detect alcohol intake and to adjust interventions, if required. Even if any alcohol use should be considered risky during pregnancy, identifying women with alcohol use disorders is important because they could need a more specific intervention than simple advice to abstain. Most screening tests have been developed and validated in male populations and focused on the long-term consequences of heavy alcohol use, so they might be inappropriate to assess consumption in pregnant women. Objective To analyze the internal reliability and validity of the alcohol screening instruments Alcohol Use Disorders Identification Test (AUDIT), Alcohol Use Disorders Identification Test -Consumption (AUDIT-C), Tolerance, Worried, Eye-Opener, Amnesia and Cut-Down (TWEAK), Rapid Alcohol Problems Screen -Quantity Frequency (RAPS-QF) and Tolerance, Annoyed, Cut-Down and Eye-Opener (T-ACE) to identify alcohol use disorders in pregnant women. Methods A total of 641 puerperal women were personally interviewed during the 48 hours after delivery. The receiver operating characteristics (ROC) curves and the sensitivity and specificity of each instrument using different cut-off points were analyzed. Results All instruments showed areas under the ROC curves above 0.80. Larger areas were found for the TWEAK and the AUDIT. The TWEAK, the T-ACE and the AUDIT-C showed higher sensitivity, while the AUDIT and the RAPS-QF showed higher specificity.

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Sustancias psicoactivas y embarazo. Estudio en una población hospitalaria de Uruguay

Cited by 2 publications

References 28 publications

A comparison of the prevalence of prenatal alcohol exposure obtained via maternal self-reports versus meconium testing: a systematic literature review and meta-analysis

A comparison of the prevalence of prenatal alcohol exposure obtained via maternal self-reports versus meconium testing: a systematic literature review and meta-analysis

Psychometric Properties of Brief Screening Tests for Alcohol Use Disorders during Pregnancy in Argentina

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