Sutureless hemostasis of a coronary sinus rupture with Hydrofit

Sutureless Repair for Iliac Vein Bleeding Using an Elastomeric Sealant

“…Pseudoaneurysms have been reported after sutureless repair for arterial pressure bleeds [11]. However, venous bleeding carries a lower risk of recurrence due to its lower pressure, as confirmed by our safety report two years postoperatively [7]. In this case, we strategically combined Hydrofit with an arterial patch, ensuring that even if Hydrofit loses its effect, the patch continues to prevent further bleeding.…”

“…It reacts rapidly with tissue water to form a robust adhesive film [6]. Unlike popular options like fibrin glue or TacoSeal (CSL Behring, King of Prussia, USA), Hydrofit thrives in moist environments and boasts precise application thanks to its viscosity, preventing unwanted spread into vessels [7]. Moreover, Hydrofit remains effective even with coagulopathy or heparinisation, as it bypasses the blood coagulation cascade altogether.…”

“…While evidence for Hydrofit 's intraoperative hemostasis is burgeoning, its long-term effects require further scrutiny. Previous studies showcase successful sutureless repair using Hydrofit in a pig model with an inferior vena cava incision [7] and a case of coronary sinus rupture in cardiac surgery [8]. An in vitro and in vivo study also reported its efficacy in achieving hemostasis in rats, when combined with Surgicel (Ethicon, Inc., Somerville, USA) [9].…”

Sutureless repair for vena cava bleeding using an elastomeric sealant in a porcine model

“…Second, venous bleeding complications have rarely been documented during remote phase. We previously reported a case of coronary sinus rupture, which was arrested using Hydrofit [ 5 ]. In this case, haemostasis was achieved using the pericardium, and the patient has been free of any complications for 2 years.…”