Sweet's syndrome: a retrospective study of 90 cases from a tertiary care center

Amouri, M.; Masmoudi, A.; Ammar, M.; Boudaya, S.; Khabir, Abdelmajid; Boudawara, T.; Turki, H.

doi:10.1111/ijd.13232

Cited by 49 publications

(40 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This notion has been supported by two findings: 1) blood vessels in lesions of longer duration are more likely to develop vasculitis than those in lesions of shorter duration, likely due to prolonged exposure to noxious metabolites; 2) immunofluorescence studies show no immunoglobulin and complement deposition in the affected blood vessels. Many authors have therefore concluded that the presence of vasculitis ought not to rule out the diagnosis of SS unless there is evidence of primary immune‐mediated vasculitis . In this context, we believe that the clinical features of SS are critical for the diagnosis as the presence of typical SS lesions strongly suggests vasculitis – reported in some cases of SS – to be a secondary event, given that primary immune‐mediated leukocytoclastic vasculitis presents with lesions clinically completely different from those observed in SS.…”

Section: Discussionmentioning

confidence: 93%

Sweet's syndrome: diagnostic criteria revisited

Nofal

Abdelmaksoud

Amer³

et al. 2017

J Deutsche Derma Gesell

View full text Add to dashboard Cite

Summary The diagnosis of Sweet's syndrome (SS) is based on a set of criteria that requires the presence of two major and at least two minor criteria. In some cases, however, the diagnosis is not as straightforward due to the absence of certain criteria. The objective of the present study was to review the clinical, histopathological, and laboratory features of the current diagnostic criteria for SS, and to evaluate their validity in the cases reported in the literature as well as in 40 patients treated at our institution. Our comprehensive review of the current criteria for SS reveals that the two major criteria have been consistently present in all cases – including ours – since the first description of SS in 1964. With regard to the minor criteria, on the other hand, there has been marked variability between different studies, and many cases failed to fulfill the requirement of showing two minor criteria. In order to simplify the diagnosis, avoid misdiagnosis, and allow for prompt treatment, we propose two sets of revised diagnostic criteria for SS. The first set comprises constant clinical and histopathological features that must be present and are by themselves sufficient for the diagnosis of SS to be established. The second set includes variable features whose absence does not warrant ruling out SS.

show abstract

Section: Discussionmentioning

confidence: 93%

Sweet's syndrome: diagnostic criteria revisited

Nofal

Abdelmaksoud

Amer³

et al. 2017

J Deutsche Derma Gesell

View full text Add to dashboard Cite

show abstract

“…A dose of 1–2 mg per day was used with regression of lesions in 1–14 days in 30 patients (68%) receiving the drug. Of the 13 patients who did not respond to colchicine initially, there was improvement following the addition of prednisone …”

Section: Potential Indications: the Newmentioning

confidence: 99%

Colchicine: an ancient drug with novel applications

et al. 2018

View full text Add to dashboard Cite

Colchicine is a treatment for gout that has been used for more than a millennium. It is the treatment of choice for familial Mediterranean fever and its associated complication, amyloidosis. The 2009 U.S. Food and Drug Administration approval of colchicine as a new drug had research consequences. Recent investigations with large cohorts of patients with gout who have been taking colchicine for years have demonstrated novel applications within oncology, immunology, cardiology and dermatology. Some emerging dermatological uses include the treatment of epidermolysis bullosa acquisita, leucocytoclastic vasculitis, aphthous stomatitis and others. In this work we relate the history and the new horizon of this ancient medicine.

show abstract

“…Patients are febrile and present erythematous welldefined and asymmetrical plaques or papules on the skin [46]. Histopathology shows absence of vasculitis, a diffuse perivascular and nodular neutrophilic infiltrate, and various degrees of edema [46,47]. Mucosal involvement is rare.…”

Section: Differential Diagnosismentioning

confidence: 99%