Sweet's Syndrome: One Disease, Multiple Faces

Kasirye, Yusuf; Danhof, Rebecca S.; Epperla, Narendranath; Garcia‐Montilla, Romel

doi:10.3121/cmr.2011.1012

Cited by 7 publications

(5 citation statements)

References 11 publications

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“…A review of the literature shows that – irrespective of underlying etiology or association – two main features have been consistently present in all reported SS cases since the first description by Sweet in 1964, including the patients in our study cohort . The first criterion is the clinical presentation of “abrupt onset of painful or tender erythematous papules, plaques, or nodules”.…”

Section: Discussionmentioning

confidence: 55%

Sweet's syndrome: diagnostic criteria revisited

Nofal

Abdelmaksoud

Amer³

et al. 2017

J Deutsche Derma Gesell

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Summary The diagnosis of Sweet's syndrome (SS) is based on a set of criteria that requires the presence of two major and at least two minor criteria. In some cases, however, the diagnosis is not as straightforward due to the absence of certain criteria. The objective of the present study was to review the clinical, histopathological, and laboratory features of the current diagnostic criteria for SS, and to evaluate their validity in the cases reported in the literature as well as in 40 patients treated at our institution. Our comprehensive review of the current criteria for SS reveals that the two major criteria have been consistently present in all cases – including ours – since the first description of SS in 1964. With regard to the minor criteria, on the other hand, there has been marked variability between different studies, and many cases failed to fulfill the requirement of showing two minor criteria. In order to simplify the diagnosis, avoid misdiagnosis, and allow for prompt treatment, we propose two sets of revised diagnostic criteria for SS. The first set comprises constant clinical and histopathological features that must be present and are by themselves sufficient for the diagnosis of SS to be established. The second set includes variable features whose absence does not warrant ruling out SS.

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Section: Discussionmentioning

confidence: 55%

Sweet's syndrome: diagnostic criteria revisited

Nofal

Abdelmaksoud

Amer³

et al. 2017

J Deutsche Derma Gesell

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“…El tratamiento de primera línea para esta patología son los corticoides en dosis de 1 mg/kg/día, que deben ser disminuidos paulatinamente entre dos y seis semanas desde su inicio, de acuerdo con la evolución clínica del paciente. 14,15 En nuestro caso, la paciente respondió favorablemente al tratamiento instaurado con corticoides.…”

Section: Discussionunclassified

Síndrome de Sweet en una niña preescolar

Pereira-Ospina

Beltrán-Hernández

Suescún-Vargas

et al. 2018

Arch Argent Pediatr

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Sweet syndrome, also known as acute febrile neutrophilic dermatosis, is an infrequent dermatological disorder in pediatrics. Clinically it is characterized by the development of papular and/or nodular lesions of a reddish-violet coloration with local hypersensitivity. We report the case of a 5-year-old female who consulted 1 month after the appearance of the lesion in the nasal arch. A skin biopsy was performed and it reported diffuse dermatitis with a predominance of neutrophil polymorphonuclear cells, epidermal necrosis and absence of vasculitis. No microorganisms were identified. It was considered compatible with Sweet syndrome. It is important to consider this diagnosis in similar clinical cases and other more frequent diagnoses must be ruled out first.

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“…The epidemiological characteristics of SS and its related conditions classify this disorder among the diseases that relate to hypersensitivity reactions to infectious, inflammatory, drug, or tumour cell antigens (15,16). Cytokines, dermal dendrocytes, and auto-antibodies might also have a role in the pathogenesis (16). Systemic corticosteroids are the gold standard of therapy for SS.…”

Section: Discussionmentioning

confidence: 99%

A Flare-up of Behcet’s Disease with Sweet’s Syndrome: A Case Report

Afsar¹,

Erkan²,

Yılmaz³

et al. 2017

West Indian Med J

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Behcet's disease (BD) is a systemic vasculitis of unknown aetiology, characterized by relapsing episodes of oral aphtous ulcers, genital ulcers, ocular lesions and skin lesions. Sweet's Syndrome is characterized by fever, neutrophilia, tender erythematous skin lesions, and histopathologic evidence of a dense neutrophilic infiltration in the papillary dermis without vasculitis and it is one of the less common skin lesions of Behcet's disease. We present a case of 44-year old woman with Behcet's disease who had erythematous and painful eruptions on her hands and forearms. She had been diagnosed as Behcet's disease after oral aphtous ulcers, genital ulcers and positive pathergy test seven years previously. An incisional biopsy of an erythematous lesion involving the forearm and laboratory work-up were performed. Based on history, clinical findings, laboratory data and histopathological examination, the patient was diagnosed as Sweet's Syndrome. Behcet's disease may manifest Sweet's Syndrome a long-time after its onset even in the absence of cardinal symptoms.

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Sweet's Syndrome: One Disease, Multiple Faces

Cited by 7 publications

References 11 publications

Sweet's syndrome: diagnostic criteria revisited

Sweet's syndrome: diagnostic criteria revisited

Síndrome de Sweet en una niña preescolar

A Flare-up of Behcet’s Disease with Sweet’s Syndrome: A Case Report

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