Sweet syndrome: a retrospective analysis of 16 patients from a tertiary care center

Sweet syndrome following SARS‐CoV‐2 infection: A unique bullous photo‐distributed presentation

“…However, it seems to be caused by a hypersensitivity reaction, leading to inflammatory cytokines secretion and neutrophil activation and migration, with tissue inflammation and damage. The unique bullous photo-distributed pattern of this case could be explained by severe inflammation with dermo-epidermal segregation, [3][4][5]7 alongside an isomorphic Koebner reaction classically described in neutrophilic dermatoses caused by UV radiation, or its direct action on neutrophil activation and migration to the skin. 9 Sometimes, paraneoplastic Sweet syndrome may occur before clinically evident neoplasia.…”

“…Photo-distribution has been described but is extremely rare. 7 There is only one case described in the literature of bullous Sweet syndrome with photodistribution, associated with a blastic crisis in a patient with myelodysplasia. 8 To the best of our knowledge, this is the first case described in association with COVID-19.…”