Sweet Syndrome in a Patient with Chronic Hepatitis C

Guo, Danny; Parsons, Laurie

doi:10.2310/7750.2014.13211

Cited by 2 publications

(4 citation statements)

References 14 publications

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“…Although hepatitis B infections are reported to be a potential trigger of SS, 4 previous case reports have associated with CHAC infection. 6 , 19 - 22 …”

Section: Discussionmentioning

confidence: 99%

“…2 Although hepatitis B infections are reported to be a potential trigger of SS, 4 previous case reports have associated with CHAC infection. 6,[19][20][21][22] In conclusion, NDDH is best understood as a distributional variant of SS in which lesions exclusively occur on the dorsal aspects of both hands. It is rare but most commonly seen as a paraneoplastic syndrome or an association with infection.…”

Section: Discussionmentioning

confidence: 99%

“…It presents with various skin manifestations, including cryoglobulinemic vasculitis, porphyria cutanea tarda, and erythema multiforme. 5,6 This case presents with NDDH associated with both MDS and CAHC infection.…”

Section: Introductionmentioning

confidence: 97%

“…It presents with various skin manifestations, including cryoglobulinemic vasculitis, porphyria cutanea tarda, and erythema multiforme. 5 , 6 …”

Section: Introductionmentioning

confidence: 99%

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Neutrophilic Dermatosis in Myelodysplastic Syndrome and Chronic Active Hepatitis C

Sharma

Johnson

Heidari

et al. 2021

Journal of Investigative Medicine High Impact Case Reports

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In this article, we describe a case of neutrophilic dermatosis of the dorsal hands (NDDH) complicated with myelodysplastic syndrome and chronic active hepatitis C infection. NDDH was first suggested by Galaria et al in 2000. After comparing features of NDDH with Sweet syndrome in terms of encompassing clinical, laboratory, and histological characteristics, it can be concluded that “distributional or localized variant” of Sweet syndrome is classified as NDDH. Early diagnosis and treatment can improve prognosis. Systemic glucocorticoids are the mainstay of treatment.

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“…Although hepatitis B infections are reported to be a potential trigger of SS, 4 previous case reports have associated with CHAC infection. 6 , 19 - 22 …”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 97%

“…It presents with various skin manifestations, including cryoglobulinemic vasculitis, porphyria cutanea tarda, and erythema multiforme. 5 , 6 …”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Neutrophilic Dermatosis in Myelodysplastic Syndrome and Chronic Active Hepatitis C

Sharma

Johnson

Heidari

et al. 2021

Journal of Investigative Medicine High Impact Case Reports

View full text Add to dashboard Cite

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Insights Into the Pathogenesis of Sweet's Syndrome

2019

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Sweet's syndrome, also known as Acute Febrile Neutrophilic Dermatosis, is a rare inflammatory condition. It is considered to be the prototype disease of neutrophilic dermatoses, and presents with acute onset dermal neutrophilic lesions, leukocytosis, and pyrexia. Several variants have been described both clinically and histopathologically. Classifications include classic Sweet's syndrome, malignancy associated, and drug induced. The cellular and molecular mechanisms involved in Sweet's syndrome have been difficult to elucidate due to the large variety of conditions leading to a common clinical presentation. The exact pathogenesis of Sweet's syndrome is unclear; however, new discoveries have shed light on the role of inflammatory signaling, disease induction, and relationship with malignancy. These findings include an improved understanding of inflammasome activation, malignant transformation into dermal infiltrating neutrophils, and genetic contributions. Continued investigations into effective treatments and targeted therapy will benefit patients and improve our molecular understanding of inflammatory diseases, including Sweet's syndrome.

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Sweet Syndrome in a Patient with Chronic Hepatitis C

Abstract: Herein, we present a case of SS in a patient with untreated chronic hepatitis C and cirrhosis but no other significant comorbidities.

Cited by 2 publications

References 14 publications

Neutrophilic Dermatosis in Myelodysplastic Syndrome and Chronic Active Hepatitis C

Neutrophilic Dermatosis in Myelodysplastic Syndrome and Chronic Active Hepatitis C

Insights Into the Pathogenesis of Sweet's Syndrome

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