Swept-Source Optical Coherence Tomography-Based Biometry: A Comprehensive Overview

Borgia, Alfredo; Raimondi, Raffaele; Sorrentino, Tania; Santoru, Francesco; Buzzi, Matilde; Borgia, Vittorio; Scorcia, Vincenzo; Giannaccare, Giuseppe

doi:10.3390/photonics9120951

Cited by 10 publications

(5 citation statements)

References 61 publications

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“…Anterior segment OCT has a relatively long wavelength that enables it to penetrate relatively deep even in non-transparent tissues (corneal infiltrates, scarring, and opacity) [53][54][55], and it can attain micrometer resolution [56,57].…”

Section: Anterior Segment Optical Coherence Tomography (As-oct)mentioning

confidence: 99%

Managing Post-Keratoplasty Astigmatism: High-Tech vs. Low-Tech Imaging Techniques for Guiding Suture Manipulation

Borgia

Romano

et al. 2023

JCM

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Astigmatism is a visually significant condition that can develop after keratoplasty. The management of post-keratoplasty astigmatism can be performed both when transplant sutures are in place and when they have been removed. Fundamental for astigmatism management is its identification and characterization in terms of type, amount, and direction. Commonly, post-keratoplasty astigmatism is evaluated through corneal tomography or topo-aberrometry; however, many other techniques can be used in case these instruments are not readily available. Here, we describe several low-tech and high-tech techniques used for post-keratoplasty astigmatism detection in order to quickly understand if it contributes to low vision quality and to determine its characteristics. The management of post-keratoplasty astigmatism through suture manipulation is also described.

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Section: Anterior Segment Optical Coherence Tomography (As-oct)mentioning

confidence: 99%

Managing Post-Keratoplasty Astigmatism: High-Tech vs. Low-Tech Imaging Techniques for Guiding Suture Manipulation

Borgia

Romano

et al. 2023

JCM

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“…SS-OCT-based biometers provide clear advantages over other technologies used in ocular biometry due to their ability to measure AL along six different axes, offering better penetration ability and extremely rapid data acquisition. [ 55 56 57 ] The deeper light penetration or long-range OCT imaging of posterior segment structures not only results in a high success rate of AL measurement but also reduces refractive PEs, making it useful for accurate refractive correction. Furthermore, the high speed of SS-OCT allows for the collection of two- or three-dimensional data in hundredths of milliseconds with high lateral and axial resolution (5 µm) while minimizing the unfavorable influence of patient eye movements on scan quality.…”

Section: Introductionmentioning

confidence: 99%

Optimization of biometry for best refractive outcome in cataract surgery

Gupta,

Pal,

Sawhney

et al. 2023

Indian Journal of Ophthalmology

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High-precision biometry and accurate intraocular lens (IOL) power calculation have become essential components of cataract surgery. In clinical practice, IOL power calculation involves measuring parameters such as corneal power and axial length and then applying a power calculation formula. The importance of posterior corneal curvature in determining the true power of the cornea is increasingly being recognized, and newer investigative modalities that can estimate both the anterior and posterior corneal power are becoming the standard of care. Optical biometry, especially using swept-source biometers, with an accuracy of 0.01–0.02 mm, has become the state-of-the-art method in biometry. With the evolution of IOL formulas, the ultimate goal of achieving a given target refraction has also moved closer to accuracy. However, despite these technological efforts to standardize and calibrate methods of IOL power calculation, achieving a mean absolute error of zero for every patient undergoing cataract surgery may not be possible. This is due to inherent consistent bias and systematic errors in the measurement devices, IOL formulas, and the individual bias of the surgeon. Optimization and personalization of lens constants allow for the incorporation of these systematic errors as well as individual bias, thereby further improving IOL power prediction accuracy. Our review provides a comprehensive overview of parameters for accurate biometry, along with considerations to enhance IOL power prediction accuracy through optimization and personalization. We conducted a detailed search in PubMed and Google Scholar by using a combination of MeSH terms and specific keywords such as “ocular biometry,” “IOL power calculations,” “prediction accuracy of refractive outcome in cataract surgery,” “effective lens position,” “intraocular lens calculation formulas,” and “optimization of A-constants” to find relevant literature. We identified and analyzed 121 relevant articles, and their findings were included.

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“…In fact, in most cases, the ophthalmic or optometry practice will have to separately procure an anterior segment OCT system, a posterior segment OCT system and an OCT biometer. This is particularly taxing for practices in low-resource settings and emerging economies, where, for example, the prevalence of cataract is higher than in developed countries [17], and the cost of the newer swept-source OCT biometers alone can be in excess of 40 k$ [18].…”

Section: Introductionmentioning

confidence: 99%

An optical beam scanner with reconfigurable non mechanical control of beam position, angle and focus for low-cost whole-eye OCT imaging

Urizar¹,

Gambra²,

Peña³

et al. 2023

Preprint

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Whole-eye optical coherence tomography (OCT) imaging is a promising tool in ocular biometry for cataract surgery planning, glaucoma diagnostics and myopia progression studies. However, conventional OCT systems are set up to perform either anterior or posterior eye segment scans and cannot easily switch between the two scan configurations without adding or exchanging optical components to account for the refraction of the eye’s optics. Even in state-of-the-art whole-eye OCT systems, the scan configurations are pre-selected and cannot be dynamically reconfigured. In this work, we present the design, optimization and experimental validation of a reconfigurable and low-cost optical beam scanner based on three electro-tunable lenses, capable of non-mechanically controlling the beam position, angle and focus. We derive the analytical theory behind its control. We demonstrate its use in performing alternate anterior and posterior segment imaging by seamlessly switching between a telecentric focused beam scan to an angular collimated beam scan. We characterize the corresponding beam profiles and record whole-eye OCT images in a model eye and in an ex vivo rabbit eye, observing features comparable to those obtained with conventional anterior and posterior OCT scanners. The proposed beam scanner reduces the complexity and cost of other whole-eye scanners and is well suited for 2-D ocular biometry. Additionally, with the added versatility of seamless scan reconfiguration, its use can be easily expanded to other ophthalmic applications and beyond.

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Swept-Source Optical Coherence Tomography-Based Biometry: A Comprehensive Overview

Cited by 10 publications

References 61 publications

Managing Post-Keratoplasty Astigmatism: High-Tech vs. Low-Tech Imaging Techniques for Guiding Suture Manipulation

Managing Post-Keratoplasty Astigmatism: High-Tech vs. Low-Tech Imaging Techniques for Guiding Suture Manipulation

Optimization of biometry for best refractive outcome in cataract surgery

An optical beam scanner with reconfigurable non mechanical control of beam position, angle and focus for low-cost whole-eye OCT imaging

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