Swimming eliminates the weight gain and abdominal fat associated with ovariectomy in the retired breeder rat despite high-fat diet selection

Melton, Sheri; Hegsted, Maren; Keenan, Michael J.; Zhang, Y.; Morris, Stacy; Bulot, Lisa; O’Neil, Carol E.; Morris, Gareth

doi:10.1006/appe.2000.0338

Cited by 21 publications

(16 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, this does not mean that body composition has not been altered with training (Latour et al). In the study by Melton et al (2000), swimming training in ovariectomized rats during an eight-week period prevented mass body gain after ovariectomy despite the increased food intake. These results demonstrate the importance of physical exercise in individuals with estrogen deprivation.…”

Section: Discussionmentioning

confidence: 98%

Effect of Physical Exercise on the Renal Structures of Ovariectomized Female LDL Knockout Mice

et al. 2018

View full text Add to dashboard Cite

SUMMARY:The reduction of ovarian function and a decrease in estrogen levels marked by menopause are related to increased susceptibility to develop dyslipidemia. These alterations in the lipid profile can have consequences in renal tissue and generate injuries that may progress to renal failure. The practice of physical activity is an important factor for the treatment and prevention of dyslipidemia and its consequences. The objective of this study is to observe the effects of physical exercise on the right kidney of ovariectomized female LDL knockout mice. Animals were submitted to moderate physical exercise, sacrificed, and the right kidney was removed for morphometric and stereological analysis. The results showed that dyslipidemia promoted a decrease in the areas of the corpuscle and renal glomerulus, in the volume density of light in both the proximal and distal convoluted tubules, and an increase in capsular space, particularly more marked in the proximal tubules. We also observed that physical exercise decreased the analyzed parameters. Our results suggest the association of physical training and dyslipidemia presents a tendency to reduce the dimensions of morphometric and stereological parameters of the kidney. These changes may be related to metabolic and physiological adaptation of renal tissue during physical exercise.

show abstract

Section: Discussionmentioning

confidence: 98%

Effect of Physical Exercise on the Renal Structures of Ovariectomized Female LDL Knockout Mice

et al. 2018

View full text Add to dashboard Cite

show abstract

“…The literature suggests possible interactions between sex hormones and body weight [16][17][18][19][20][21] . In this study, the elevation of estradiol and serum progesterone decline in females undergoing biliopancreatic duct ligation may suggest a relationship between hyperbilirubinemia and the pituitary-gonadal axis.…”

Section: Groupsmentioning

confidence: 99%

“…Besides hyperbilirubinemia, one could still think that sex steroids would likely influence murine body weight 16,17,18 . In previous work in the same line of investigation, it was observed that young adult female rats submitted to oophorectomy had increased body weight in relation to the only laparotomized ones, with weight gain from the ninth week of castration on 24 .…”

Section: Groupsmentioning

confidence: 99%

“…In this sense, the interaction of sex hormones seems to influence the hepatobiliary functions [12][13][14][15] . The relationship between sex steroids and weight variation has been postulated by several authors [16][17][18][19][20][21] . It is known that from the third decade of life the body starts declining functional abilities, especially in women after menopause, who tend to increase in body fat and decrease in basal metabolism.…”

Section: Introduction Introduction Introduction Introductionmentioning

confidence: 98%

“…At menopause, there is addition of 800g body weight each 18 . With the discovery of leptin, a hormone regulator of obesity, we question its possible interaction with the metabolism of bilirubin [22][23][24] .…”

Section: Introduction Introduction Introduction Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Influência da icterícia colestática na variação ponderal em modelo experimental

Vasconcellos¹,

Alberti²,

Romeiro³

et al. 2012

Rev. Col. Bras. Cir.

View full text Add to dashboard Cite

OBJETIVO: Avaliar a influência da icterícia colestática na variação ponderal. MÉTODOS: Foram utilizados 64 ratos adultos, distribuídos em seis grupos: F1 (n=6) - fêmeas normais, F2 (n=6) - fêmeas laparotomizadas, F3 (n=20) - fêmeas ictéricas, M1 (n=6) - machos normais, M2 (n=6) - machos laparotomizados, M3 (n=20) - machos ictéricos. A icterícia foi obtida com ligadura e secção do ducto biliopancreático. Os pesos dos animais foram registrados semanalmente, durante sete semanas. No 14º dia de experimento, dosaram-se as bilirrubinas séricas e os hormônios gonadais. Após a sétima semana, realizou-se estudo histológico do fígado. RESULTADOS: Os animais dos grupos F3 e M3 apresentaram bilirrubinas elevadas e diminuição da massa corpórea, quando comparados com os demais grupos. As diferenças ponderais foram significativas a partir da quarta semana entre as fêmeas e da quinta semana entre os machos. Nos animais ictéricos houve aumento do estradiol e diminuição da progesterona e da testosterona total. Septos de fibroses perivenular e periportal, colangite e hiperplasia de ductos biliares ocorreram no fígado dos animais ictéricos. Nenhum animal apresentou cirrose. CONCLUSÃO: Ocorreu redução do peso corpóreo murino em presença de icterícia colestática em ambos os sexos.

show abstract

Macronutrient Selection in Experimental Animals

Kanarek

2004

CP Neuroscience

View full text Add to dashboard Cite

To address the question of how animals choose diets from an array of nutritionally different foods, researchers have designed experiments in which animals are provided with separate sources of the three macronutrients, protein, fat and carbohydrate. These experiments are useful for investigating the neuroanatomical and neurochemical mechanisms involved in food choice, as well as for assessing the effects of changes in physiological status (e.g., pregnancy; lactation and increased energy expenditure) or disease states (e.g., diabetes; and obesity) on nutrient intakes.

show abstract

Swimming eliminates the weight gain and abdominal fat associated with ovariectomy in the retired breeder rat despite high-fat diet selection

Cited by 21 publications

References 30 publications

Effect of Physical Exercise on the Renal Structures of Ovariectomized Female LDL Knockout Mice

Effect of Physical Exercise on the Renal Structures of Ovariectomized Female LDL Knockout Mice

Influência da icterícia colestática na variação ponderal em modelo experimental

Macronutrient Selection in Experimental Animals

Contact Info

Product

Resources

About