2023
DOI: 10.1002/phar.2872
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Switching from intravenous vancomycin to oral antibiotics reduces adverse events in a retrospective cohort of outpatients with orthopedic infections

Chanah K. Gallagher,
Heather Cummins,
Russell J. Benefield
et al.

Abstract: IntroductionVancomycin is frequently used for prolonged courses in treating osteoarticular infections despite a high rate of adverse drug events (ADE). The objective of this study was to evaluate the safety and effectiveness of transitioning to oral therapy compared to continuing parenteral vancomycin in patients with orthopedic infections.MethodsWe conducted a single‐center, retrospective cohort study of patients with orthopedic infections discharged on parenteral vancomycin with a planned duration of at leas… Show more

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