We discuss the status of different determinations of α s , motivating a precise and reliable computation from lattice QCD. In order to suppress perturbative errors, the non-perturbative computation has to reach high energy scales µ. Such results already exist in the SF-scheme for N f = 0, 2 [1,2] and N f = 3 [3]. We recently added the running with four massless flavours in a range of α from about 0.07 to 0.3 . It is based on our recent determination of the Sheikholeslami Wohlert coefficient in the four-flavour theory.