Symbiogenesis, gradualism, and mitochondrial energy in eukaryote origin

Martin, William

doi:10.18054/pb.v119i3.5694

Cited by 36 publications

(39 citation statements)

References 146 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Archaeal ribosomes in the cytosol could however equally be the result of a gradualist origin of eukaryotes from archaea [31,32] or symbiogenesis involving an archaeal host for the origin of mitochondria [33,34]. Ribosomes only comprise about 50 proteins and three RNAs, while the proteins used for phylogenetic classification are only about 30 in number, or roughly 1% of an average prokaryotic genome [35].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Bacterial genes outnumber archaeal genes in eukaryotic genomes

Bruckner

Martin

2019

Preprint

View full text Add to dashboard Cite

AbstractThe origin of eukaryotes is one of evolution’s most important transitions, yet it is still poorly understood. Evidence for how it occurred should be preserved in eukaryotic genomes. Based on phylogenetic trees from ribosomal RNA and ribosomal proteins, eukaryotes are typically depicted as branching together with or within archaea. This ribosomal affiliation is widely interpreted as evidence for an archaeal origin of eukaryotes. However, the extent to which the archaeal ancestry of genes for the cytosolic ribosomes of eukaryotic cells is representative for the rest of the eukaryotic genome is unknown. Here we have clustered 19,050,992 protein sequences from 5,443 bacteria and 212 archaea with 3,420,731 protein sequences from 150 eukaryotes spanning six eukaryotic supergroups to identify genes that link eukaryotes exclusively to bacteria and archaea respectively. By downsampling the bacterial sample we obtain estimates for the bacterial and archaeal proportions of genes among 150 eukaryotic genomes. Eukaryotic genomes possess a bacterial majority of genes. On average, eukaryotic genes are 56% bacterial in origin. The majority drops to 53% in eukaryotes that never possessed plastids, and increases to 61% in photosynthetic eukaryotic lineages, where the cyanobacterial ancestor of plastids contributed additional genes to the eukaryotic genome, reaching 67% in higher plants. Intracellular parasites, which undergo reductive evolution in adaptation to the nutrient rich environment of the cells that they infect, relinquish bacterial genes for metabolic processes. In the current sample, this process of adaptive gene loss is most pronounced in the human parasite Encephalitozoon intestinalis with 86% archaeal and 14% bacterial derived genes. The most bacterial eukaryote genome sampled is rice, with 67% bacterial and 33% archaeal genes. The functional dichotomy, initially described for yeast, of archaeal genes being involved in genetic information processing and bacterial genes being involved in metabolic processes is conserved across all eukaryotic supergroups.

show abstract

Section: Introductionmentioning

confidence: 99%

“…c) Symbiogenesis at the origin of eukaryotes. d) Symbiogenesis at the origin of eukaryotes plus plastds at the origin of the plant kingdom and secondary symbiotic events among algae (see refs [6,23,28,34]…”

mentioning

confidence: 99%

Bacterial genes outnumber archaeal genes in eukaryotic genomes

Bruckner

Martin

2019

Preprint

View full text Add to dashboard Cite

show abstract

“…One influential view has it that eukaryogenesis was initiated and driven by a key “horizontal” event: the endosymbiotic acquisition of the mitochondrion, which is thought to have provided massive energetic benefits by increasing membrane surface area for ATP‐synthesis (Martin, Garg, & Zimorski, ). There have been several recent challenges to this view (e.g., Booth & Doolittle, ; Hampl, Čepička, & Eliás, ; Lynch & Marinov, ; Pittis & Gabaldón, ), along with vigorous rebuttals (see, e.g., Lane & Martin, , 2016; Martin, ; McBride, ). Regardless of how this debate is ultimately resolved, adjudicating competing hypotheses of eukaryogenesis requires that we take into account key cellular features involved in making a metabolic living: phagocytosis (cell membrane innovations that allow for the engulfment and ingestion of food sources) or mitochondria.…”

Section: Toward a Richer Horizontal Perspective On The History Of Lifementioning

confidence: 99%

“…One influential view has it that eukaryogenesis was initiated and driven by a key "horizontal" event: the endosymbiotic acquisition of the mitochondrion, which is thought to have provided massive energetic benefits by increasing membrane surface area for ATP-synthesis (Martin, Garg, & Zimorski, 2015). There have been several recent challenges to this view (e.g., Booth & Doolittle, 2015;Hampl, Čepička, & Eliás, 2019;Lynch & Marinov, 2015;Pittis & Gabaldón, 2016), along with vigorous rebuttals (see, e.g., Lane & Martin, 2016, 2016Martin, 2017;McBride, 2018 metabolism an unperturbed background condition that simply supported classic microevolutionary forces that gradually constructed the eukaryotic cell? Whatever the answers to these questions, a metabolic perspective is critical to an understanding of the origin and evolution of this new cell type, which was of crucial importance for the evolution of complex multicellular life.…”

Section: Toward a Richer Horizontal Perspective On The History Of mentioning

confidence: 99%

Metabolic and microbial perspectives on the “evolution of evolution”

Powell

O’Malley

2019

J Exp Zool Pt B

View full text Add to dashboard Cite

Identifying and theorizing major turning points in the history of life generates insights into not only world‐changing evolutionary events but also the processes that bring these events about. In his treatment of these issues, Bonner identifies the evolution of sex, multicellularity, and nervous systems as enabling the “evolution of evolution,” which involves fundamental transformations in how evolution occurs. By contextualizing his framework within two decades of theorizing about major transitions in evolution, we identify some basic problems that Bonner's theory shares with much of the prevailing literature. These problems include implicit progressivism, theoretical disunity, and a limited ability to explain major evolutionary transformations. We go on to identify events and processes that are neglected by existing views. In contrast with the “vertical” focus on replication, hierarchy, and morphology that preoccupies most of the literature on major transitions, we propose a “horizontal” dimension in which metabolism and microbial innovations play a central explanatory role in understanding the broad‐scale organization of life.

show abstract

“…We also have stars in our team, well known to the scientific community, e.g. Ivan Đikić (4), Enrico Schleiff (5), Zoran Radić (6) and William F. Martin (7,8) to mention just some of them (all laureates of the Spiridion Brusina medal from recent years).…”

Section: Fifa World Cup -What Do They Have In Common?mentioning

confidence: 99%

120th Volume of Periodicum Biologorum and 21st FIFA World Cup – what do they have in common?

Jelaska¹

2018

Period Biol

View full text Add to dashboard Cite

Symbiogenesis, gradualism, and mitochondrial energy in eukaryote origin

Cited by 36 publications

References 146 publications

Bacterial genes outnumber archaeal genes in eukaryotic genomes

Bacterial genes outnumber archaeal genes in eukaryotic genomes

Metabolic and microbial perspectives on the “evolution of evolution”

120th Volume of Periodicum Biologorum and 21st FIFA World Cup – what do they have in common?

Contact Info

Product

Resources

About