Abstract. The inclusive two-particle cross section for the production of large PT photons and opposite side charged hadrons in proton-proton collisions is examined in detail in the framework of QCD. The model, with the parametrization as in our previous work, agrees with the measured single photon spectra. Quantitative predictions are made for twoparticle distributions to be measured at the ISR. The contributions due to the photon bremsstrahlung and the effects coming from the intrinsic constituent motion are estimated. It is shown that indeed the direct subprocess gluon + quark -* photon + quark gives the dominant contribution in the experimentally relevant region of phase space, and that direct information about the gluon structure function can be obtained from such measurements.