Symmetrical Acrokeratoderma: A Case Report and Literature Review

Abstract

The current study explores a case of symmetrical acrokeratoderma, and related literature is reviewed. A 27-year-old male presented with brownish-black plaques distributed symmetrically on the dorsum of the hands and feet for 3 years, and white maceration of the lesions was observed after immersion in water. The patient was diagnosed with symmetrical acrokeratoderma, and Hirudoid ointment was topically administered twice a day for a month. The symptoms were partially alleviated, and the patient is currently under follow-up observation.

Symmetrical acrokeratoderma: a case series

“…5) Lesions regain their original state after drying, the lesions are usually asymptomatic and 6) The typical histopathology features include epidermal hyperkeratosis, acanthosis and superficial perivascular lymphohistiocytic infiltration. [1][2][3][4] Chen et al, proposed to change the name of the disease from symmetrical acrokeratoderma to pigmented carpotarsal hyperkeratosis or hyperkeratosis nigricans carpi et tarsi based on distribution of the lesions and clinical features. 3 White macerations of the skin lesions after exposure of hands with water and sweating is not specific for symmetrical acrokeratoderma.…”

“…This condition is common in young Asian males. [1][2][3][4][5] It is characterised by asymptomatic brownish-black plaques distributed symmetrically over dorsum of hand and flexural surface of wrist. There is varying involvement of feet, ankle, knee and elbow.…”

“…There is varying involvement of feet, ankle, knee and elbow. [1][2][3][4] SAK does not involve palms and soles. White maceration of lesions after contact with water is remarkable feature of SAK.…”

“…White maceration of lesions after contact with water is remarkable feature of SAK. [1][2][3][4] Worsening of skin lesions is noticed during summer with complete remission in winter. 1,4 SAK has emerged as new entity during last few years.…”

“…[1][2][3][4] Worsening of skin lesions is noticed during summer with complete remission in winter. 1,4 SAK has emerged as new entity during last few years. Many names like pigmented aqua-exacerbated symmetrical acral hyperkeratosis, pigmented carpotarsal hyperkeratosis and hyperkeratosis nigricans carpi et tarsi have been suggested for symmetrical acrokeratoderma by different authors.…”