In this article, we explain how to extend the Lie symmetry analysis method for n-coupled system of fractional ordinary differential equations in the sense of Riemann-Liouville fractional derivative. Also, we systematically investigated how to derive Lie point symmetries of scalar and coupled fractional ordinary differential equations namely (i) fractional Thomas-Fermi equation, (ii) Bagley-Torvik equation, (iii) two-coupled system of fractional quartic oscillator, (iv) fractional type coupled equation of motion and (v) fractional Lotka-Volterra ABC system.The dimensions of the symmetry algebras for the Bagley-Torvik equation and its various cases are greater than 2 and for this reason we construct optimal system of one-dimensional subalgebras. In addition, the exact solutions of the above mentioned fractional ordinary differential equations are explicitly derived wherever possible using the obtained symmetries.