Sympathetic Nervous System Physiology and Pathophysiology in Coping with the Environment

Goldstein, David S.; Eisenhofer, Graeme

doi:10.1002/cphy.cp070402

Cited by 8 publications

(8 citation statements)

References 172 publications

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“…The AL model evolved from the stress-response work of Selye (1955), who argued that stress is the nonspecific response of the body to a demand, regardless of whether the demand resulted in pleasant or unpleasant conditions. Selye’s model of responses to stress, which suggests that the body adapts to stress via single-point tuning (e.g., changing blood oxygen levels), was challenged by subsequent research that demonstrated that there was a great variety in physiological responses depending on the different cues and situations facing individuals (Goldstein & Eisenhofer, 2000). Selye also relied on the concept of homeostasis, which refers to the body’s attempt to maintain a stable internal environment through a complex system of feedback mechanisms.…”

Section: The Physiological Basis Of Stress: the Allostatic Load Modelmentioning

confidence: 99%

Work Stress and Employee Health

Ganster

Rosen

2013

Journal of Management

641

308

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Research examining the relationship between work stress and well-being has flourished over the past 20 years. At the same time, research on physiological stress processes has also advanced significantly. One of the major advances in this literature has been the emergence of the Allostatic Load model as a central organizing theory for understanding the physiology of stress. In this article, the Allostatic Load model is used as an organizing framework for reviewing the vast literature that has considered health outcomes that are associated with exposure to psychosocial stressors at work. This review spans multiple disciplines and includes a critical discussion of management and applied psychology research, epidemiological studies, and recent developments in biology, neuroendocrinology, and physiology that provide insight into how workplace experiences affect well-being. The authors critically review the literature within an Allostatic Load framework, with a focus on primary (e.g., stress hormones, anxiety and tension) and secondary (e.g., resting blood pressure, cholesterol, body mass index) mediators, as well as tertiary disease end points (e.g., cardiovascular disease, depression, mortality). Recommendations are provided for how future research can offer deeper insight into primary Allostatic Load processes that explain the effects of workplace experiences on mental and physical well-being.

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Section: The Physiological Basis Of Stress: the Allostatic Load Modelmentioning

confidence: 99%

Work Stress and Employee Health

Ganster

Rosen

2013

Journal of Management

641

308

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“…The experience of stress is common to all living organisms and both human and animal studies indicate that vulnerability to drug abuse is enhanced by stressful events. A stress response is elicited when sensations and observations do not match existing or anticipated perceptions and expectations [9]. A primary endocrine response to stress is the secretion of glucocorticoids (GCs) [corticosterone in rats; cortisol CORT in humans] through the activation of the hypothalamic–pituitary–adrenal axis [10].…”

Section: Introductionmentioning

confidence: 99%

Interactions between methamphetamine and environmental stress: role of oxidative stress, glutamate and mitochondrial dysfunction

Tata

Yamamoto

2007

Addiction

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Aims Methamphetamine is an amphetamine derivative that is abused increasingly world-wide at an alarming rate over the last decade. Pre-clinical and human studies have shown that methamphetamine is neurotoxic to brain dopamine and serotonin. Other lines of study indicate that stress enhances the vulnerability to drug abuse. The purpose of this review is to shed light on the biochemical similarities between methamphetamine and stress in an effort to highlight the possibility that prior exposure to stress may interact with methamphetamine to exacerbate neurotoxicity. Methods A review of the literature on methamphetamine and stress was conducted that focused on the common neurotoxic and biochemical consequences of methamphetamine administration and stress exposure. Results Experimental findings of a large number of studies suggest that there are parallels between stress and methamphetamine with regard to their ability to increase glutamate release, produce a metabolic compromise and cause oxidative damage. Conclusion A combination of methamphetamine administration and stress can act synergistically and/or additively to cause or augment toxicity in brain regions such as striatum and hippocampus.

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“…También es importante indicar que los estudios científicos del estrés en seres humanos demuestran la necesidad de tomar en consideración los factores ambientales, culturales, actitudinales y rasgos de personalidad que cumplen un rol mediador y modulador en la respuesta fisiológica del estrés (Goldstein & Eisenhofer, 2000). Asimismo, está empíricamente demostrado que la respuesta del estrés puede ser diferente cuando se tiene en cuenta el sexo del individuo.…”

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El estrés crónico y la Terapia Cognitiva Centrada en Mindfulness: Una nueva dimensión en psiconeuroinmunología

Moscoso

2010

Persona

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Sympathetic Nervous System Physiology and Pathophysiology in Coping with the Environment

Cited by 8 publications

References 172 publications

Work Stress and Employee Health

Work Stress and Employee Health

Interactions between methamphetamine and environmental stress: role of oxidative stress, glutamate and mitochondrial dysfunction

El estrés crónico y la Terapia Cognitiva Centrada en Mindfulness: Una nueva dimensión en psiconeuroinmunología

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