Sympathetic ophthalmia following cyclodialysis cleft repair

Heydon, Peter; Hooper, Claire; Lawlor, Mitchell; Lee, Anne

doi:10.1111/ceo.13488

Cited by 3 publications

(3 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Few cases of SO have also been reported following closed globe injuries or blunt trauma, 25–27 intraocular foreign body, 28 chemical injuries, 29 and even thermal eye injuries. 30 Various surgical procedures can cause SO, including transscleral cyclophotocoagulation, 31 scleral buckling, 32 proton beam radiation, 33 helium ion therapy for choroidal melanoma, 34 ruthenium plaque for iris melanoma, 35 enucleation, 36 penetrating keratoplasty, 37 conjunctival flap procedure for perforated corneal ulcer, 38 phakic intraocular lens implantation, 39 evisceration, 40 iridectomy, 41 trabeculectomy, 42 repair of cyclodialysis cleft, 43 and paracentesis. 44…”

Section: Epidemiologymentioning

confidence: 99%

Sympathetic Ophthalmia: Where Do We Currently Stand on Treatment Strategies?

Paulbuddhe¹,

Addya²,

Gurnani³

et al. 2021

OPTH

View full text Add to dashboard Cite

Section: Epidemiologymentioning

confidence: 99%

Sympathetic Ophthalmia: Where Do We Currently Stand on Treatment Strategies?

Paulbuddhe¹,

Addya²,

Gurnani³

et al. 2021

OPTH

View full text Add to dashboard Cite

“…The incidence of sympathetic ophthalmia is estimated to be 0.2-0.5% following trauma and 0.01% after ocular surgery [9,10]. Reports of sympathetic ophthalmia have been documented following a multitude of types of ocular surgery, including cataract surgery, trabeculectomy, cyclodestruction, cyclodialysis cleft repair, iridectomy, pars plana vitrectomy (PPV), primary scleral buckle surgery, evisceration and retinal laser photocoagulation [11][12][13][14][15][16][17]. There has been an increasing number of case reports and series of sympathetic ophthalmia following vitreoretinal surgery [18][19][20][21].…”

Section: Incidence and Characteristics Of Sympathetic Opthalmia Follo...mentioning

confidence: 99%

Recent advances in diagnosis and management of sympathetic ophthalmia

Fromal

Swaminathan

Soares

et al. 2021

Current Opinion in Ophthalmology

View full text Add to dashboard Cite

Purpose of reviewSympathetic ophthalmia is a bilateral granulomatous uveitis that occurs following unilateral trauma or surgery and is sight-threatening in the contralateral eye. Despite significant potential morbidity, disease remains poorly understood. Variable presentations and clinical courses, as well as a lack of definitive diagnostic laboratory tests can complicate the diagnosis and result in delayed treatment, which can beget permanent vision loss. This review focuses on recent advances in areas of pathophysiology, classification, diagnosis and treatment. Recent findingsSympathetic ophthalmia is thought to involve a cell-mediated immune response to retinal and uveal antigens exposed through trauma or surgery. Multiple mechanisms have been implicated, including activation of the interleukin-23/IL-17 pathway. Ongoing emphasis is placed on early disease recognition and prompt treatment with multimodal imaging. Multiple authors advocate for the routine use of optical coherence tomography (OCT) for screening and disease monitoring. Systemic steroids and steroids sparingimmunosuppressive agents remain the mainstay of treatment.

show abstract

“…It has been estimated that sympathetic ophthalmia occurs in 0.02–0.05% of patients with ocular trauma and in 0.01% of patients undergoing ophthalmic surgery [ 6 ]. Because of its rarity, most of the clinical and optical coherence tomography (OCT) studies of sympathetic ophthalmia were case reports or small case-series [ 7 , 8 ]. Previous OCT studies of small numbers of patients initially revealed SRD with choroidal thickening in the acute stage of PSO [ 9 – 11 ].…”

Section: Introductionmentioning

confidence: 99%

Clinical classification, visual outcomes, and optical coherence tomographic features of 48 patients with posterior sympathetic ophthalmia

Zhuang

Zhang

et al. 2022

Orphanet J Rare Dis

View full text Add to dashboard Cite

Background To investigate the clinical manifestations, visual outcomes and optical coherence tomographic (OCT) features of patients with posterior sympathetic ophthalmia (PSO). Methods We performed a retrospective review of 48 patients diagnosed with PSO between January 2013 and December 2019. We compared the clinical and OCT features among different clinical types of PSO. Results PSO could be classified into two types according to whether the fundus exhibited serous retinal detachment (SRD) or multifocal choroiditis (MFC). There were 41 patients (85.4%) with SRD and 7 patients (14.6%) with MFC. The latent period of patients with MFC was significantly longer than that of patients with SRD (P = 0.002). The final visual acuity of patients with MFC was significantly worse than that of patients with SRD (P = 0.0001). In patients with acute SRD, OCT revealed that the mean height of retinal detachment in the fovea was 528.8 ± 437.5 μm. After treatment, the retina reattached in all patients and the band structures of the outer retina were restored in most patients (92.7%). In patients with acute MFC, the OCT images revealed inflammatory lesions on the retinal pigment epithelium layer. After treatment, the OCT images showed hyperreflective fibrosis of the lesions and loss of the outer retinal band structures in all patients. Conclusions We found that PSO could be classified according to the presence of SRD or MFC. The visual prognosis differed significantly between these types of PSO. OCT imaging is useful for clinical classification and monitoring of retinal changes after treatment.

show abstract

Sympathetic ophthalmia following cyclodialysis cleft repair

Cited by 3 publications

References 3 publications

Sympathetic Ophthalmia: Where Do We Currently Stand on Treatment Strategies?

Sympathetic Ophthalmia: Where Do We Currently Stand on Treatment Strategies?

Recent advances in diagnosis and management of sympathetic ophthalmia

Clinical classification, visual outcomes, and optical coherence tomographic features of 48 patients with posterior sympathetic ophthalmia

Contact Info

Product

Resources

About