This article aims to introduce readers to a recent research topic, sympathetic skin response (SSR). The article provides information on the historical development of sympathetic response since the late 19th century. The article also includes information on the identification of naturally existed amplitude and latency values and classification based on these values, international measurement techniques with the studies conducted within the last hundred years, the factors effecting these measurements according to the studies conducted, and criteria used in the evaluation of the data obtained. In addition, information is given about the studies that have been made.