Symptom clusters and quality of life in China patients with lung cancer undergoing chemotherapy

Wang, Dandan; Fu, Jianfang

doi:10.4314/ahs.v14i1.8

Cited by 49 publications

(70 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…We interpreted the symptom clusters according to the underlying similarities of the symptoms. The fatigue–sleep symptom cluster consisted of symptoms including fatigue, disturbed sleep and drowsiness, which is similar to the previous findings (Chen & Tseng, ; Karabulut, Erci, Ozer, & Ozdemir, ; Wang & Fu, ). Research reported that this symptom cluster is affected by pro‐inflammatory cytokines (e.g., interleukin‐1, interleukin‐6, TNF‐α and interferon‐α; Ji et al, .…”

Section: Discussionsupporting

confidence: 90%

“…Similar to previous studies (Albusoul, Berger, Gay, Janson, & Lee, ; Wang & Fu, ; Ward, Leutwyler, Dunn, & Miaskowski, ), the chemoradiotherapy side‐effect symptom cluster consists of four symptoms of nausea, vomiting, loss of appetite and dry mouth. Chemoradiotherapy stimulates the vomiting centre through nerve conduction or directly stimulates the cerebral cortical pathway, causing patient's nausea and vomiting.…”

Section: Discussionsupporting

confidence: 76%

See 1 more Smart Citation

Symptom clusters and related factors in oesophageal cancer patients 3 months after surgery

Guo

Wang

Yin

et al. 2019

Journal of Clinical Nursing

View full text Add to dashboard Cite

Aim To explore symptom clusters experienced by patients with oesophageal cancer 3 months after surgery and examine whether symptom clusters are related to demographic, clinical and quality of life variables. Background There are multiple symptoms in patients with oesophageal cancer after surgery, which seriously affect their quality of life. Exploring the mechanics of concurrent symptoms such as symptom clusters may facilitate the development of strategies to reduce the impact of these symptoms and improve quality of life. Design Cross‐sectional survey. The STROBE Statement was chosen as the EQUATOR checklist. Methods A convenience sample of 128 oesophageal cancer patients was followed up at 3 months after surgery. Participants completed the demographic questionnaire, the M. D. Anderson Symptom Inventory for Gastrointestinal Cancer, the Functional Assessment of Cancer Therapy‐General and the Connor‐Davidson Resilience Scale. Exploratory factor analysis, stepwise regression and correlation analysis were applied. Results Four symptom clusters were identified: dysphagia–psychological, chemoradiotherapy side‐effect, digestive tract reconstruction and fatigue–sleep. Gender, stage of disease and resilience influenced the dysphagia–psychological symptom cluster. Gender, stage of disease, resilience and treatment were significant factors affecting the chemoradiotherapy side‐effect and fatigue–sleep symptom clusters. Gender, stage of disease, resilience and anastomotic position were significant factors influencing the digestive tract reconstruction symptom cluster. The correlations between symptom clusters and quality of life were significant, with the highest correlation between the dysphagia–psychological cluster and quality of life. Conclusions Nurses should pay more attention to symptom management in patients with oesophageal cancer 3 months after surgery by focusing on four symptom clusters. It is necessary to implement individualised care depending on the influence factors including gender, stage of disease, resilience, treatment and anastomotic position. Relevance to clinical practice These findings will help develop targeted interventions to facilitate further symptom management for transitional nursing from the peri‐operative phase to long‐term rehabilitation.

show abstract

Section: Discussionsupporting

confidence: 90%

Section: Discussionsupporting

confidence: 76%

Symptom clusters and related factors in oesophageal cancer patients 3 months after surgery

Guo

Wang

Yin

et al. 2019

Journal of Clinical Nursing

View full text Add to dashboard Cite

show abstract

“…13 – 14 One of the earliest studies of symptom clusters in lung cancer patients used the dimension of symptom distress to empirically derive four symptom clusters (i.e., emotional and physical suffering, gastrointestinal distress, respiratory distress, malaise) in women with advanced lung cancer receiving various types of treatment. 15 In contrast, the dimension of symptom severity was utilized to identify symptom clusters in four studies of lung cancer patients after diagnosis, 16 during CTX, 17 during chemoradiation, 18 and in a heterogeneous sample of lung cancer patients at various time points during their disease. 19 Across these four studies, one 16 to three 18 clusters were identified.…”

Section: Introductionmentioning

confidence: 99%

Differences in Symptom Clusters Identified Using Ratings of Symptom Occurrence vs. Severity in Lung Cancer Patients Receiving Chemotherapy

Wong

Cooper

Paul

et al. 2017

Journal of Pain and Symptom Management

View full text Add to dashboard Cite

Context An important question in symptom clusters research is whether the number and types of symptom clusters vary based on the specific dimension of the symptom experience used to create the clusters. Objectives Given that lung cancer patients undergoing chemotherapy (CTX) report an average of 14 co-occurring symptoms and studies of symptom clusters in these patients are limited, the purpose of this study, in lung cancer patients undergoing CTX (n=145), was to identify whether the number and types of symptom clusters differed based on whether symptom occurrence rates or symptom severity ratings were used to create the clusters. Methods A modified version of the Memorial Symptom Assessment Scale was used to assess for the occurrence and severity of 38 symptoms, one week after the administration of CTX. Exploratory factor analysis was used to extract the symptom clusters. Results Both the number and types of symptom clusters were relatively similar using symptom occurrence rates or symptom severity ratings. Five symptom clusters were identified using both symptom occurrence rates and severity ratings (i.e., sickness behavior, lung cancer-specific, psychological, nutritional, epithelial). Across these two dimensions, the specific symptoms within each of the symptom clusters were relatively similar. Conclusions Identification of symptom clusters in patients with lung cancer may assist with the development of more targeted symptom management interventions. Future studies are warranted to determine if symptom clusters change over a cycle of CTX in patients with lung cancer.

show abstract

“…Some complaints/symptoms during the administration of chemotherapy are actually side effects of chemotherapy and some are the result of the underlying disease; while in some cases they overlap. (11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22) Radiotherapy works differently on certain aspects of quality of life as well as the individual symptoms. In this study, radiation therapy reduced pain and coughing; and it was observed that hair loss was less pronounced in this group of patients.…”

Section: Discussionmentioning

confidence: 99%

Quality of life in lung cancer patients due to treatment

2016

View full text Add to dashboard Cite

Lung cancer is the second most common cancer in men and women. Survival has not significantly improved despite new therapeutic possibilities. Therefore, in patients with end-stage disease, the primary goal is to preserve the quality of life as long as possible. The study included patients divided into four groups depending on the treatment: treated with chemotherapy, radiotherapy, a combination of chemotherapy and radiotherapy and patients treated with symptomatic therapy. Each group consists of 30 subjects. We measured quality of life using a questionnaire of the European Association for the Study and Treatment of Cancer in addition of no.13 for lung cancer (EO-RTC QLQ C30 + LC13), which is validated and translated in the native language and includes 43 questions. Patients who are on symptomatic therapy have the worst quality of life, and all aspects of normal functioning are the most disturbed when compared to patients treated with other therapeutic modalities. Quality of life is best for patients who are treated with chemotherapy. Any modality of treatment, especially chemotherapy, is superior to the use of only symptomatic treatment.

show abstract

Symptom clusters and quality of life in China patients with lung cancer undergoing chemotherapy

Cited by 49 publications

References 20 publications

Symptom clusters and related factors in oesophageal cancer patients 3 months after surgery

Symptom clusters and related factors in oesophageal cancer patients 3 months after surgery

Differences in Symptom Clusters Identified Using Ratings of Symptom Occurrence vs. Severity in Lung Cancer Patients Receiving Chemotherapy

Quality of life in lung cancer patients due to treatment

Contact Info

Product

Resources

About