Symptom diagnostics based on clinical records

Jong, Marianne de; Punt, Marja; Groot, E. de; Hielkema, Tjitske; Struik, M.H.L.; Minderaa, Ruud B.; Hadders‐Algra, Mijna

doi:10.1007/s00787-008-0726-4

Cited by 3 publications

(1 citation statement)

References 18 publications

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“…If there is any pathology that causes disability, such as cerebral palsy or muscular dystrophy, it is classified as neurologically abnormal. 22 The test–retest, intrarater, and interrater reliability of the Modified Touwen Neurological Examination are reported as good-to-moderate level. Reliability for the coordination and fine manipulation areas is moderate, and for the other areas that were evaluated, they are good.…”

Section: Methodsmentioning

confidence: 95%

Minor Neurological Dysfunction: A Comparative Study in Pediatrics with Different Types of Focal Epilepsy

Cam,

Tekin-Orgun,

Soysal-Acar

et al. 2024

Journal of Pediatric Epilepsy

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Epilepsy is a disorder that occurs as a result of abnormal neuronal discharges in the brain and affects approximately 1% of children. Sensorimotor function impairments that are related to minor neurological deficits may be seen even in children diagnosed with epilepsy solely. This study aims to determine the type and areas of minor neurological dysfunction (MND) in children with Self-Limited Focal Epilepsy (SeLFE) and to compare the children with Self-Limited Epilepsy with Centrotemporal Spikes (SeLECTS) and SeLFE without SeLECTS. Fifty-six children diagnosed with epilepsy (28 SeLECTS and 28 SeLFE without SeLECTS) were included in the study. Both groups consisted of 13 girls and 15 boys. The mean ages of SeLECTS and SeLFE without SeLECTS groups were 9.68 ± 1.63 and 9.32 ± 1.62, respectively. A Modified Touwen Neurological Examination was performed to determine the type and areas of MND. There were no differences between the groups regarding MND type, coordination, fine manipulation, sensory, and involuntary movement areas (p > 0.05). It should be considered that children with SeLECTS may be neurologically affected as much as children with other types of epilepsy. Long-term problems due to epilepsy may be minimized by short-term neurodevelopmental follow-ups.

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Section: Methodsmentioning

confidence: 95%

Minor Neurological Dysfunction: A Comparative Study in Pediatrics with Different Types of Focal Epilepsy

Cam,

Tekin-Orgun,

Soysal-Acar

et al. 2024

Journal of Pediatric Epilepsy

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Minor neurological dysfunction in children with dyslexia

Punt¹,

Jong²,

Groot

et al. 2010

Develop Med Child Neuro

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Minor neurological dysfunction in children with autism spectrum disorder

Jong¹,

Punt²,

Groot

et al. 2011

Developmental Medicine &Amp; Child Neurology

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AIM The aim of this study was to improve the understanding of brain function in children with autism spectrum disorder (ASD) in relation to minor neurological dysfunctions (MNDs).METHOD We studied MNDs in 122 children (93 males, 29 females; mean age 8y 1mo, SD 2y 6mo) who, among a total cohort of 705 children (513 males, 192 females; mean age 9y, SD 2y 0.5mo) referred to a regional outpatient non-academic psychiatric centre in the Netherlands, were diagnosed with ASD after an extensive multidisciplinary psychiatric assessment. Children with clear neurological abnormalities (e.g. cerebral palsy or spina bifida) were excluded from the study. MNDs were assessed in all 705 children using the Touwen examination method. Special attention was paid to the severity and type of MND. Data of the children with ASD were compared with neurological morbidity data of children with other psychiatric disorders and with children in the general population, who were born at Groningen University Hospital between 1975 and 1978. RESULTS Seventy-four percent of the children with ASD showed complex MNDs compared with 52% of the children with other psychiatric disorders and 6% of the reference group (v 2 =18.0, p<0.001; v 2 =937.5, p<0.001 respectively). Specific dysfunctions frequently encountered in ASD were dysfunctional posture and muscle tone, fine manipulative disability, dyscoordination, and excessive associated movements.CONCLUSION These findings suggest a contribution of dysfunctional supraspinal networks involving multiple parts of the brain in the pathogenesis of ASD. This is consistent with findings from neuroimaging studies, and highlights the importance of neurological examinations in paediatric psychiatric assessments.Autism spectrum disorder (ASD) is an early childhood-onset neurodevelopmental disorder characterized by delay and deviations in the development of social, communicative, and cognitive skills, and is associated with a very wide range of syndrome expression. The term 'ASD' encompasses children with the full autism syndrome as well as variants, such as Asperger syndrome, and pervasive developmental disorders not otherwise specified.Children with ASD are often described as 'clumsy' 1-3 or as having motor deficits. [4][5][6] In addition, psychiatric classification systems cite stereotypes in motor behaviour (e.g. hand-flicking or -twisting) as criteria for classifying ASD. 7,8 However, little is known about the neurological background of the clumsiness. Some studies report that children with ASD frequently exhibit soft neurological signs, 9 but only rarely are details of these signs reported. Others report motor deficits but do not refer to the neurological background of these deficits. [4][5][6] Neuroimaging studies of ASD shed some light on the neural substrate of ASD. Abnormalities are described in the following neural systems: [10][11][12] (1) the cerebellum -loss of Purkinje cells and anomalies in the shape of the cerebellum and vermix; 13,14 (2) the cerebral cortex -hyperplasia of grey and white matter of ...

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Symptom diagnostics based on clinical records

Cited by 3 publications

References 18 publications

Minor Neurological Dysfunction: A Comparative Study in Pediatrics with Different Types of Focal Epilepsy

Minor Neurological Dysfunction: A Comparative Study in Pediatrics with Different Types of Focal Epilepsy

Minor neurological dysfunction in children with dyslexia

Minor neurological dysfunction in children with autism spectrum disorder

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