Exploring Discomfort during ChemotherapyAsian Pac J Cancer Prev, 24 (2), 459-465 surgery, to remove a cancerous tumor. The main goal of adjuvant chemotherapy is to lower the chance that cancer will return and improve the outcome of first-line treatment. (National Comprehensive Cancer Network, 2019).Discomfort for breast cancer patients might be felt during adjuvant chemotherapy simultaneously with a side effect from previous treatment, such as after surgery. Adjuvant therapy can consist of physical discomfort, including pain, fatigue, difficulty sleeping, nausea and vomiting, taste disorders, hair loss, constipation, diarrhea, sexual dysfunction, loss of appetite, and weight loss.