Symptom profile and outcome of delirium associated with alcohol withdrawal syndrome: A study from India

Grover, Sandeep; Sharma, Akhilesh; Kate, Natasha; Mattoo, Surendra Kumar; Basu, Debasish; Chakrabarti, Subho; Malhotra, Savita

doi:10.1111/j.1521-0391.2013.12063.x

Cited by 12 publications

(11 citation statements)

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“…This study used a combined data set of existing related databases from two countries, Ireland 20 29-34 and India. [35][36][37][38][39][40][41][42][43] All research took place between 2008 and 2020 inclusive. Raters for data included in this study were trained by an expert with over 20 years' experience in the field of delirium research (DM), through training workshops in both Ireland and India using well validated assessment methods for these clinical populations as outlined below.…”

Section: Subjects and Designmentioning

confidence: 99%

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How do delirium motor subtypes differ in phenomenology and contributory aetiology? a cross-sectional, multisite study of liaison psychiatry and palliative care patients

et al. 2021

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ObjectivesTo investigate whether delirium motor subtypes differ in terms of phenomenology and contributory aetiology.DesignCross-sectional study.SettingInternational study incorporating data from Ireland and India across palliative care, old age liaison psychiatry and general adult liaison psychiatry settings.Participants1757 patients diagnosed with delirium using criteria from the Diagnostic and Statistical Manual of Mental Disorders, Fourth edition (DSM IV).Primary and secondary outcome measuresHyperactive, mixed and hypoactive delirium subtypes were identified using the abbreviated version of the Delirium Motor Subtype Scale. Phenomenology was assessed using the Delirium Rating Scale Revised. Contributory aetiologies were assessed using the Delirium Aetiology Checklist (DEC), with a score >2 indicating that the aetiology was likely or definitely contributory.ResultsHypoactive delirium was associated with dementia, cerebrovascular and systemic infection aetiologies (p<0.001) and had a lower overall burden of delirium symptoms than the other motor subtypes. Hyperactive delirium was associated with younger age, drug withdrawal and the DEC category other systemic aetiologies (p<0.001). Mixed delirium showed the greatest symptom burden and was more often associated with drug intoxication and metabolic disturbance (p<0.001). All three delirium motor subtypes had similar levels of impairment in attention and visuospatial functioning but differed significantly when compared with no subtype (p<0.001).ConclusionsThis study indicates a pattern of aetiology and symptomatology of delirium motor subtypes across a large international sample that had previously been lacking. It serves to improve our understanding of this complex condition and has implications in terms of early detection and management of delirium.

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Section: Subjects and Designmentioning

confidence: 99%

“…20 33 34 General adult CL psychiatry This group consisted of consecutive referrals to a general adult CL psychiatry service at the Post Graduate Institute Open access for Medical Research in Chandigarh, India, who were diagnosed with delirium at the time of assessment. [35][36][37][38][39][40][41][42][43]…”

Section: Palliative Carementioning

confidence: 99%

How do delirium motor subtypes differ in phenomenology and contributory aetiology? a cross-sectional, multisite study of liaison psychiatry and palliative care patients

et al. 2021

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“…Five studies have primarily focused on patients with AWD (►Table 5). 30,31,[58][59][60] One study evaluated the service model for patients with AWD and reported that compared with Delirium Research in India Grover et al…”

Section: Studies Focusing On Patients With Alcohol-withdrawal Deliriummentioning

confidence: 99%

“…the emergency services treatment group alone, emergency services plus comprehensive inpatient addiction treatment group had fewer relapses. 59 Other studies have focused on risk factors associated with AWD, 58 symptom profile of delirium, 30 and factor structure of symptom profile. 31 One study evaluated the genetic variations associated with the development of delirium tremens and reported that delirium tremens was significantly associated with presence of T allele (GT and TT; [rs1824024]) of muscarinic cholinergic receptor 2 (CHRM2).…”

Section: Studies Focusing On Patients With Alcohol-withdrawal Deliriummentioning

confidence: 99%

Delirium Research in India: A Systematic Review

Grover

Kathiravan

Dua

2021

JNRP

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Delirium is the most common psychiatric diagnoses encountered in patients with various medical-surgical illnesses, in all the treatment set-ups, with relatively higher incidence and prevalence in the intensive care units. As delirium is encountered in multiple specialties, it is important to understand the research on this diagnosis. This study aims to assess the research output involving patients of delirium from India. A comprehensive search was undertaken using Medline (PubMed) and other databases. Search words included were “delirium,” “delirious,” “delirium tremens” AND “India.” No filters were used. Internet and hand searches yielded 305 articles. Out of these articles, 151 had the terms “delirium,” “delirious,” “delirium tremens” in the title and these were included for the review. Additionally, 14 articles were included for the review, although these did not have these terms in the title, but delirium was one of the major outcome parameters in these studies. Majority of the papers were original articles (n = 81), and these were followed by, case reports (n = 58), review articles (n = 10), letter to the editor (not as case reports but as a communication; n = 13), editorials (n = 2) and one clinical practice guideline. Most of the original papers have either focused on epidemiology (incidence, prevalence, outcome, etc.), symptom profile, with occasional studies focusing on effectiveness of various pharmacological interventions. There is a dearth of research in the field of delirium from India. There is a lack of studies on biomarkers, evaluation of nonpharmacological interventions, and evaluation of prevention strategies. It is the need of the hour to carry out more studies to further our understanding of delirium in the Indian context.

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“…Этому в значительной степени способствует также высокий уровень сопутствующих заболеваний в этой группе населения [16]. Так, среди пациентов с алкогольным делирием, поступивших в хирургические отделения, летальность составляет 13 % [17], а при черепно-мозговой травме -11 % [15]. Пациенты с алкогольным делирием в анамнезе имеют более высокую смертность, чем те, у кого отмечается только алкогольная зависимость и не было зафиксировано проявлений делирия [9].…”

Section: диагностика и интенсивная терапия церебральной недостаточносunclassified

Delirium tremens: early diagnosis and intensive care guidelines. Review

Muronov

2020

Annals of Critical Care

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Alcoholic delirium is a formidable complication of severe alcohol withdrawal syndrome. It is often formed in patients of hospitals and departments of anesthesiology and intensive care, as a result of the forced cessation of alcohol consumption. Its formation is associated with an increase in the length of hospital stay and mortality. The review discusses modern approaches to the diagnosis, especially early, of this condition, its intensive care and methods of non-drug correction.

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Symptom profile and outcome of delirium associated with alcohol withdrawal syndrome: A study from India

Cited by 12 publications

References 20 publications

How do delirium motor subtypes differ in phenomenology and contributory aetiology? a cross-sectional, multisite study of liaison psychiatry and palliative care patients

How do delirium motor subtypes differ in phenomenology and contributory aetiology? a cross-sectional, multisite study of liaison psychiatry and palliative care patients

Delirium Research in India: A Systematic Review

Delirium tremens: early diagnosis and intensive care guidelines. Review

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