Symptomatic and Morphological Differences between Choroidal Excavations

Kumano, Yuji; Nagai, Hirofumi; Enaida, Hiroshi; Ueno, Akifumi; Matsui, Takaaki

doi:10.1097/opx.0b013e31828736f3

Cited by 27 publications

(18 citation statements)

References 8 publications

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“…In our series, FFA confirmed acute CSCR in 4 eyes. By comparing these 4 eyes with the nonconforming-type cases in the literature [2,3,5,15], the following differences were noted: first, the retinal detachment was always within the excavation in nonconforming cases, while it usually exceeded the excavation in CSCR cases; second, the fine lines of the ELM and the IS/OS at the detached area were slightly above the normal counterparts in CSCR cases, while they were below those of the normal counterparts in nonconforming cases; third, changes in PRE were more common and prominent in CSCR cases; and fourth, CSCR eyes could be either type 1 or 2 (there were more type 2 in our series), while nonconforming-type cases described in previous reports were mostly type 1 [2,3,5,15]. And since recent study found that choroidal thickness was increased in focal choroidal excavation patients if complicated by CSC, so this could be another point that could be helpful in the differentiating [12].…”

Section: Discussionmentioning

confidence: 99%

Clinical and optic coherence tomography findings of focal choroidal excavation in Chinese patients

et al. 2014

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BackgroundTo describe the clinical and optical coherence tomography (OCT) features of focal choroidal excavation in Chinese patients.MethodsRetrospectively, thirty-seven eyes (in 31 patients) that demonstrated focal choroidal excavation on spectral-domain OCT were collected. Their clinical characteristics and other features were also collected and analyzed.ResultsIn total, 42 focal choroidal excavations were identified in 31 patients, including 25 unilateral and 6 bilateral (37 eyes). The abnormal changes in these eyes with choroidal excavation were more prominent at the outer part of the neuro-retina, the retinal pigment epithelium (RPE) and the choroid. The average transverse diameter and depth of the excavations were 670.8 μm and 106.9 μm, respectively. In addition to the conforming and nonconforming types, the excavations could also be classified into 2 types according to their shape: type 1 – small with a sharp, cut-down contour; and type 2 – slightly larger with a gradual edge. The transverse diameter/depth ratio of the two types were significantly different (type1: 4.57 ± 1.65, type 2: 10.0 ± 5.2; p = 0.000). Four central serous chorioretinopathy (CSCR) cases were confirmed by fluorescein angiography; in these cases, the retinal detachment was larger than the area of excavation, and the inner segment/outer segment (IS/OS) and external limiting membrane (ELM) were above those of the normal part. Concomitant CNV was also found in another 2 cases.ConclusionsFocal choroidal excavation was not uncommon in Chinese patients. The choroid and the RPE at the excavation were impaired or vulnerable to other damage. Additionally, OCT might be useful in the differentiation between nonconforming excavations and ones with CSCR.

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Section: Discussionmentioning

confidence: 99%

Clinical and optic coherence tomography findings of focal choroidal excavation in Chinese patients

et al. 2014

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“…12 Kumano ve ark., ekskavasyon alanında vasküler anormallik olduğunu ve hiperreflektan dokunun Bruch membranı ve suprakoroidal lamina arasındaki anormal adezyonlar olabileceğini bildirmişlerdir. 13 Benzer hiperreflektan doku görünümü olgu 3'te de mevcuttur. Ayrıca, olgu 1 ve 2'nin FFA'sında lezyon alanına uyan bölgedeki koroid floresanın çevresine göre daha hipofloresan olarak izlenmesi altta yatan koroid hipoperfüzyonundan ya da oluşan skar dokusunun koroidal vasküler yapıyı bozmasından kaynaklanıyor olabilir.…”

Section: Discussionunclassified

Focal Choroidal Excavation

Özateş¹,

Tekin²,

Teke³

2018

Turkiye Klinikleri J Ophthalmol

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oroidal ekskavasyon, ilk kez 2006 yılında Jampol ve ark. tarafından bildirilmiş; posterior stafilom, skleral ektazi ya da sistemik hastalık birlikteliği olmayan, koroidin ve retinanın fokal çukurlaşması ile karakterize lezyonlar olarak tanımlanmıştır. 1,2 Genel olarak fundus muayenesinde renk değişikliği olan retina pigment epiteli (RPE) değişiklikleri olarak bulgu vermektedir. Lezyon genellikle asemptomatik olmakla birlikte, santral seröz korioretinopati (SSKR) ya da polipoidal koroidal vaskülopati (PKV) gibi beraber görülebilen durumlarda görme keskinliğinde azalmaya ve metamorfopsi şikâyetlerine neden olabilmektedir. 3,4 Bu olgu serisinde, fokal koroidal ekskavasyon (FKE) tanısı alan 3 olgunun klinik özelliklerinin, muayene bulgularının ve izlem sürecindeki değişikliklerin incelenmesi amaçlanmışır.

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“…However, it is considered that FCE could be an embryonic developmental disorder or an acquired pathology. Some authors hypothesize that FCE is a congenital malformation while as others theorize that it might due to the failure of chorioretinal development in the embryonic stage, micro staphyloma, congenital focal choroidal dysplasia, focal choroidal atrophy caused by congenital or acquired choroiditis [2,3,11,[26][27][28][29][30][31][32][33] . Focal choroidal excavation often does not appear in mono/ polychromatic fundus photography, fundus angiography or ophthalmoscopy and it might be only detected using OCT.…”

Section: Discussionmentioning

confidence: 99%

“…In 2011, this tomographical entity was called as FCE by Margolis et al [2] . FCE is defined as a focal area of intrachoroidal concavity in the macula detected in OCT in an eye with preserved visual acuity and normal fundus without a posterior staphyloma or scleral ectasia, a history of trauma, inflammatory/ infectious or vascular disease in retina or choroid [2][3][4][5][26][27][28][29][30][31][32][33] . Although the FCE is a relatively stationary lesion, it can cause the CNV [6][7][8] .…”

Section: Discussionmentioning

confidence: 99%

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The Frequency Of Focal Choroidal Excavation Detected By Optical Coherence Tomography

Turgut¹

2017

International Journal of Ophthalmic Research

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involvement were also evaluated as control cases in this study. The medical records of ten patients with FCEs detected by SDOCT were reviewed. The causes, frequency, associated diseases, types, size and shape, associated SDOCT pathologies, SDOCT findings of the FCEs in ten cases were evaluated and commented on. RESULTS: The FCE was detected in ten eyes of ten cases. Of the patients with FCE, 4 (40%) were women and 6 (60%) were men. The ages of patients were ranged between 63 to 76 years (median 66.1 years). Bilateral FCE was not detected. The FCE was detected in one eye with w-AMD (1/368 patients), in two eyes with active CSCR (2/214), in one with AVMD (1/32 patients) and in 5 eyes of the control (idiopathic FCE; 5/228). CONCLUSIONS: FCE may be detected in various macular chorioretinal diseases. However, it should be considered that FCE might be idiopathic. INTRODUCTIONChoroidal excavation is a new optical coherence tomography (OCT) finding firstly described by Jampol et al [1] . Later, it was called focal choroidal excavation (FCE) by Margolis et al [2] . FCE is characterized by focal concavity at the RPE-choriocapillaris line in the choroid in an OCT scan, with a good visual acuity, and normal appearance of the overlying retina. In the FCE cases, there is no history of trauma and current or prior retinal or choroidal vascular or infectious disease [3][4][5] . It is considered that this lesion often remains stable [2][3][4][5] . However, some lesions may be related to the development of CNV [6][7][8] .It has been reported that FCE may occur in various macular diseases such as age-related macular degeneration (AMD), central serous chorioretinopathy (CSCR), epiretinal membrane ABSTRACT AIM: To determine the frequency and the causes of focal choroidal excavation (FCE) detected by spectral domain optical coherence tomography (SDOCT), and to comment on its clinical importance. MATERIALS AND METHODS:In this study, 632 eyes of the patients with untreated wet age-related macular degeneration (w-AMD, n = 368), central serous chorioretinopathy (CSCR, n = 214), Vogt-Koyanagi-Harada Disease (VKHD, n = 3), adult vitelliform macular dystrophy (AVMD, n = 32), Best vitelliform macular dystrophy (BVMD, n = 2) and other macular dystrophies and specific maculopathies (n = 13) were retrospectively reviewed for the presence of the FCE. Additionally, 228 unaffected fellow eyes without obvious macular pathology of the cases with unilateral

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Symptomatic and Morphological Differences between Choroidal Excavations

Cited by 27 publications

References 8 publications

Clinical and optic coherence tomography findings of focal choroidal excavation in Chinese patients

Clinical and optic coherence tomography findings of focal choroidal excavation in Chinese patients

Focal Choroidal Excavation

The Frequency Of Focal Choroidal Excavation Detected By Optical Coherence Tomography

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