Symptomatic sarcoidosis of the stomach

Chinitz, Marvin A.; Brandt, Lawrence J.; Frank, Michael S.; Frager, David; Sablay, Leonarda B.

doi:10.1007/bf01308419

Cited by 53 publications

(35 citation statements)

References 12 publications

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“…disease [4] and narrowing of stomach that resembles scirrhous carcinoma. The stomach may appear smooth, tubular, aperistaltic, and immobile to palpation.…”

Section: Discussionmentioning

confidence: 98%

Gastric sarcoidosis

et al. 1997

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Sarcoidosis of the gastrointestinal tract is uncommon even though involvement of the liver, spleen, and adenopathy are becoming recognizable entities on computed tomography (CT). Involvement of the stomach, the most common site of sarcoidosis of the gastrointestinal tract, is usually associated with pulmonary disease. The radiologic appearances of gastric involvement are variable. Positive biopsies may be obtained in a radiologically normal stomach. Ulceration resembling peptic ulcer disease may occur, and mucosal enlargement may be minor, diffusely nodular, or significant enough to mimic Menetrier disease. In its most dramatic form, a linitis plastica appearance resembling scirrhous carcinoma has been reported.

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“…disease [4] and narrowing of stomach that resembles scirrhous carcinoma. The stomach may appear smooth, tubular, aperistaltic, and immobile to palpation.…”

Section: Discussionmentioning

confidence: 98%

Gastric sarcoidosis

et al. 1997

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“…In diffuse form, fibrosis due to granulomatous infiltration, widespread mucosal thickening, rigidity, and reduction in lumen size have been reported (26-28). Antral narrowing and deformity owing to gastric mucosal fold enlargement may lead to gastric outlet obstruction mimicking Menetrier's disease (29,30). The most common imaging finding of upper GI involvement is a segmental linitis plastica-type appearance which should be differentiated from gastric carcinoma (29).…”

Section: Gastrointestinal Tractmentioning

confidence: 99%

“…Antral narrowing and deformity owing to gastric mucosal fold enlargement may lead to gastric outlet obstruction mimicking Menetrier's disease (29,30). The most common imaging finding of upper GI involvement is a segmental linitis plastica-type appearance which should be differentiated from gastric carcinoma (29). Extrinsic compression from extensively enlarged retroperitoneal lymph nodes may also occur throughout the GI tract.…”

Section: Gastrointestinal Tractmentioning

confidence: 99%

Abdominal sarcoidosis: cross-sectional imaging findings

Gezer¹,

Başara²,

Altay³

et al. 2015

Diagn Interv Radiol

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Sarcoidosis is a multisystem inflammatory disease of unknown etiology. The lungs and the lymphoid system are the most commonly involved organs. Extrapulmonary involvement is reported in 30% of patients, and the abdomen is the most common extrapulmonary site with a frequency of 50%-70%. Although intra-abdominal sarcoidosis is usually asymptomatic, its presence may affect the prognosis and treatment options. The lesions are less characteristic and may mimick neoplastic or infectious diseases such as lymphoma, diffuse metastasis, and granulomatous inflammation. The liver and spleen are the most common abdominal sites of involvement. Sarcoidosis of the gastrointestinal system, pancreas, and kidneys are extremely rare. Adenopathy which is most commonly found in the porta hepatis, exudative ascites, and multiple granulomatous nodules studding the peritoneum are the reported manifestations of abdominal sarcoidosis. Since abdominal sarcoidosis is less common and long-standing, unrecognized disease can result in significant morbidity and mortality. Imaging contributes to diagnosis and management of intra-abdominal sarcoidosis. In this report we reviewed the cross-sectional imaging findings of hepatobiliary, gastrointestinal, and genitourinary sarcoidosis.

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“…Corticosteroid therapy produces a dramatic clinical response in about 66% of patients with systemic gastric sarcoidosis [23]. Prednisone 20-40 mg/d can be started with gradual dose reduction.…”

Section: Treatmentmentioning

confidence: 99%

“…Patients with disseminated GI tract sarcoidosis may also report diarrhea due to involvement of small or large bowel. About 25% of patients with gastric sarcoidosis also can present with symptoms of upper GI bleeding [23,24]. The different types of gastric sarcoidosis are as follows.…”

Section: Gastric Sarcoidosismentioning

confidence: 99%

Sarcoidosis of Gastrointestinal Tract: A Rare Disease

et al. 2007

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Gastrointestinal (GI) tract sarcoidosis is an uncommon form of sarcoidosis. The GI tract can be involved as an isolated disease as a part of systemic sarcoidosis. Clinical manifestations of esophageal, gastric, small bowel, colon, and appendicular sarcoidosis are discussed in this review. The differential diagnosis of GI sarcoidosis is extensive. Other granulomatous diseases of the GI tract, like tuberculosis, fungal infections, parasitic diseases, inflammatory bowel disease, and Whipple's disease, should be excluded before making the diagnosis of GI sarcoidosis. Corticosteroid therapy is effective in treatment of GI sarcoidosis. Surgical intervention may be necessary in patients with bowel obstruction, perforation, or massive hemorrhage.

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Symptomatic sarcoidosis of the stomach

Cited by 53 publications

References 12 publications

Gastric sarcoidosis

Gastric sarcoidosis

Abdominal sarcoidosis: cross-sectional imaging findings

Sarcoidosis of Gastrointestinal Tract: A Rare Disease

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