Symptomatic Treatment for Progressive Multiple Sclerosis

Rice, Claire M; Wilkins, Alastair

doi:10.1007/978-1-4471-2395-8_8

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2013

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“…A wide variety of symptomatic drugs and interventions, beyond the scope of this article but excellently reviewed elsewhere7 8 can be of major benefit in patients with progressive MS—whether for pain, fatigue, depression, bladder incontinence, impotence, spasticity or tonic spasms. The first symptomatic drugs to improve mobility are beginning to emerge, if of limited efficacy,9 while treatments to help ataxia, tremor and nystagmus remain very poor.…”

Section: Managementmentioning

confidence: 99%

Primary progressive multiple sclerosis: progress and challenges

Rice

Cottrell

Wilkins

et al. 2013

J Neurol Neurosurg Psychiatry

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Primary progressive multiple sclerosis (MS) has long been recognised as presenting great difficulties to our management of what is increasingly a treatable neurological disease. Here we review some basic and clinical aspects of primary progressive MS, and describe how the disorder in fact offers powerful insights and opportunities for better understanding multiple sclerosis, and from a practical perspective an invaluable clinical substrate for studying and treating progressive disability in MS. Difficult hurdles remain, however, and these too are reviewed.

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Section: Managementmentioning

confidence: 99%