Symptomatic vasospasm and outcomes following aneurysmal subarachnoid hemorrhage: a comparison between surgical repair and endovascular coil occlusion

Rabinstein, Alejandro A.; Pichelmann, Mark; Friedman, Jonathan A.; Piepgras, David G.; Nichols, Douglas A.; McIver, Jon I.; Toussaint, L. Gerard; McClelland, Robyn L.; Fulgham, Jimmy R.; Meyer, Fredric B.; Atkinson, John L.D.; Wijdicks, Eelco F. M.

doi:10.3171/jns.2003.98.2.0319

Cited by 152 publications

(73 citation statements)

References 28 publications

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“…[1][2][3][4] The current strategies for preventing vasospasm comprise the systemic administration of the calcium channel blocker nimodipine. [5][6][7] Moreover, the use of intracisternal thrombolysis 8 and the intracisternal application of nicardipine-prolonged implants 9,10 demonstrated effectiveness in preventing cerebral vasospasm.…”

mentioning

confidence: 99%

Intra-Arterial Nimodipine for Severe Cerebral Vasospasm after Aneurysmal Subarachnoid Hemorrhage: Influence on Clinical Course and Cerebral Perfusion

Hänggi¹,

Turowski²,

Beseoglu³

et al. 2008

AJNR Am J Neuroradiol

118

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mentioning

confidence: 99%

Intra-Arterial Nimodipine for Severe Cerebral Vasospasm after Aneurysmal Subarachnoid Hemorrhage: Influence on Clinical Course and Cerebral Perfusion

Hänggi¹,

Turowski²,

Beseoglu³

et al. 2008

AJNR Am J Neuroradiol

118

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“…Only 51% of the patients suffering angiographic CVS presented with TCD criteria for CVS. In a consecutive series of 415 patients, Rabinstein et al [10] observed an incidence of symptomatic CVS in 39% in patients who underwent clipping compared to 30% in patients who underwent coiling. The authors demonstrated that patients with better clinical grades (WFNS I-III) at hospital admission were less to suffer symptomatic CVS when treated with endovascular techniques compared with surgical treatment.…”

Section: Incidence Of Vasospasm and Risk Factorsmentioning

confidence: 99%

“…Moreover, differences in outcome between patients undergoing endovascular and surgical treatment have not been extensively studied [5][6][7][8][9][10][11][12]. In terms of comparison of quality of life between patients treated with endovascular and surgical techniques, only one study has been published so far [13].…”

Section: Introductionmentioning

confidence: 99%

Incidence of Vasospasm, Outcome, and Quality of Life after Endovascular and Surgical Treatment of Ruptured Intracranial Aneurysms: Results of a Single-Center Prospective Study in Switzerland

Hofmann

Marbacher

Jakob

et al. 2011

ISRN Vascular Medicine

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Background. Outcome after endovascular versus surgical treatment of ruptured aneurysms is still controversial. The aim of this study was to analyze the incidence of cerebral vasospasm (CVS), outcome, and quality of life in patients undergoing endovascular or surgical treatment. Methods. This single-center prospective study included all patients undergoing aneurysm occlusion over a one-year period. All patients underwent postinterventional CT scan, TCD, and angiography on day 9 ± 2 . Outcome (Barthel Index, NIHSS, mRS, MMSE) was evaluated at 6 and 12 weeks. Quality of life (EuroQoL, SF-12) was assessed at 6 months. Results. A total of 66 patients were included. The overall mortality due to CVS was 9.9%, and higher in the surgical (14.6%) than in the endovascular group (4%). The incidence of symptomatic (29.2% versus 24%) and angiographic (70.7% versus 52%) CVS was not statistically significant different between the two groups. No differences in outcome or quality of life (SF-12) could be demonstrated. Conclusions. The outcome and quality of life of patients undergoing endovascular or surgical treatment seems not to significantly differ if demographic, radiological, and intensive care parameters are similar. A trend toward lower incidence of CVS in patients undergoing endovascular treatment was observed.

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“…Despite the limited success achieved by these approaches, 26-38% patients either develop sequelae or die of severe symptomatic vasospasm [12][13] . The success of the current treatment strategies against delayed cerebral vasospasm after SAH remain inconsistent, and seem to have variable effects on the outcome 14 . Despite its clinical significance and the extensive research efforts placed into elucidating its pathogenesis and therapy, vasospasm remains as an incompletely understood and important clinical problem.…”

Section: Introductionmentioning

confidence: 99%

Expression of Sphingosine-1-phosphate (S1P) on the cerebral vasospasm after subarachnoid hemorrhage in rabbits

et al. 2015

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PURPOSE: To demonstrate the relationship between of sphingosine-1-phosphate (S1P) expression and subarachnoid hemorrhage (SAH). METHODS:The basilar arteries from a "double-hemorrhage" rabbit model of SAH were used to investigate the relation between S1P expression and SAH. Various symptoms, including blood clots, basilar artery cross-sectional area, and S1P phosphatase expression were measured at day 3, 5, 7, 9. RESULTS:The expression of S1P was enhanced in the cerebral vasospasm after subarachnoid hemorrhage in the rabbits. And S1P expression was consistent with the basilar artery cross-sectional area changes at day 3, 5, 7, 9.CONCLUSION: Sphingosine-1-phosphate expression in the cerebral arterial may be a new indicator in the development of cerebral vasospasm after subarachnoid hemorrhage and provide a new therapeutic method for SAH.

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Symptomatic vasospasm and outcomes following aneurysmal subarachnoid hemorrhage: a comparison between surgical repair and endovascular coil occlusion

Cited by 152 publications

References 28 publications

Intra-Arterial Nimodipine for Severe Cerebral Vasospasm after Aneurysmal Subarachnoid Hemorrhage: Influence on Clinical Course and Cerebral Perfusion

Intra-Arterial Nimodipine for Severe Cerebral Vasospasm after Aneurysmal Subarachnoid Hemorrhage: Influence on Clinical Course and Cerebral Perfusion

Incidence of Vasospasm, Outcome, and Quality of Life after Endovascular and Surgical Treatment of Ruptured Intracranial Aneurysms: Results of a Single-Center Prospective Study in Switzerland

Expression of Sphingosine-1-phosphate (S1P) on the cerebral vasospasm after subarachnoid hemorrhage in rabbits

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