Symptoms of Depression in Individuals With Obstructive Sleep Apnea May Be Amenable to Treatment With Continuous Positive Airway Pressure

Schwartz, Daniel P.; Kohler, William C.; Karatinos, Gillian

doi:10.1378/chest.128.3.1304

Cited by 96 publications

(61 citation statements)

References 29 publications

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“…It is based on a series of key aspects of behaviour and emotion in which the respondent rates items on a four-point scale (0-3) with a potential range of total scores from 0 to 63. The BDI-II has previously been utilised to assess levels of depression in OSA patients [3][4][30][31], and is used in this study to provide an empirical measure of the levels of depression in both patient groups and controls. The Profile of Mood States (POMS) is a well-established measure of mood disorder [32].…”

Section: Methodsmentioning

confidence: 99%

“…Sleepiness, on the other hand, is more often used to describe a subjective experience or feeling of difficulty remaining awake, or through objective measurement demonstrating increased sleep propensity [24]. The misconception of fatigue and sleepiness in patients attending sleep laboratories may contribute to measurement errors, and lead to people with depression presenting for evaluation for sleep disorders [4]. An indirect association between OSA and depression has been observed in previous studies, mediated by daytime sleepiness [13], or fatigue [17-18; 25], independent of disease severity.…”

Section: Statistical Manual Of Mental Disorders (Dsm-iv) Criteria Fomentioning

confidence: 99%

“…Depressive symptoms are commonly reported by patients with Obstructive Sleep Apnea (OSA), and higher rates of depressive symptomatology in OSA patients have been observed in a number of prevalence studies when compared to the general population [1][2][3][4][5]. Between 15% and 56% of OSA patients are diagnosed with a depressive disorder [2,[6][7][8] compared to only 6.6% of the general population [9].…”

Section: Introductionmentioning

confidence: 99%

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The contribution of fatigue and sleepiness to depression in patients attending the sleep laboratory for evaluation of obstructive sleep apnea

et al. 2010

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2 ABSTRACTPurpose: A high prevalence of depressive symptomatology has been reported amongst sufferers of Obstructive Sleep Apnea (OSA), but it remains unclear as to whether this is due to their OSA or other factors associated with the disorder. The current study aimed to assess the incidence and aetiology of depression in a community sample of individuals presenting to the sleep laboratory for diagnostic assessment of OSA.Methods: Forty-five consecutive individuals who presented to the sleep laboratory were recruited; of those, 34 were diagnosed with OSA and eleven were primary snorers with no clinical or laboratory features of OSA. Nineteen control subjects were also recruited. Patients and controls completed the Beck Depression Inventory (BDI), the Profile of Mood States (POMS), and the Epworth Sleepiness Scale (ESS) to assess their mood and sleepiness, prior to their polysomnography.Results: All patients reported significantly more depressive symptoms compared to healthy controls, regardless of their degree of OSA. There were no significant differences between OSA patients and primary snorers on any of the mood and selfrated sleepiness measures. Depression scores were not significantly associated with any of the nocturnal variables. Regression analysis revealed that the POMS fatigue subscale explained the majority of the variance in subjects" depression scores. Conclusions:Fatigue was the primary predictor of the level of depressive symptoms in patients who attended the sleep laboratory, regardless of the level of severity of sleep-disordered breathing. When considering treatment options, practitioners should be aware of the concomitant occurrence of depressive symptoms and fatigue in patients presenting with sleep complaints, which may not be due to a sleep disorder.

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Section: Methodsmentioning

confidence: 99%

Section: Statistical Manual Of Mental Disorders (Dsm-iv) Criteria Fomentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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The contribution of fatigue and sleepiness to depression in patients attending the sleep laboratory for evaluation of obstructive sleep apnea

et al. 2010

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“…24 Our survey also supports previous reports that people with sleep apnea may present to their primary care physicians with depression and that treatment of sleep apnea may ameliorate depression. 27 Therefore, patients reporting sleep disturbance need to be thoroughly evaluated for mood disorders.…”

mentioning

confidence: 99%

Sleep Problems in Primary Care: A North Carolina Family Practice Research Network (NC-FP-RN) Study

Alattar¹,

Harrington²,

Mitchell³

et al. 2007

The Journal of the American Board of Family Medicine

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Background:The prevalence and nature of sleep disorders in primary care has not been widely studied. As part of a survey conducted in 5 family practice offices in North Carolina, we screened adult patients for sleep syndromes and sought to ascertain which demographic status and health status were associated with these disorders.Methods: We approached 2963 consecutive adults who presented for office visits to the 5 study practices. The 4-page study questionnaire, which was available in English and Spanish, included items on insomnia, excessive daytime sleepiness, obstructive sleep apnea syndrome, and restless legs syndrome. Analyses evaluated the relationship between sleep syndromes and demographic factors, health status, and disability.Results: We enrolled 1935 patients (65.3% response rate). More than half reported excessive daytime sleepiness, one third had insomnia, more than 25% had symptoms of restless legs syndrome, and 13% to 33% reported obstructive sleep apnea syndrome symptoms. Participants who rated their health as poor reported significantly higher rates of all sleep disturbance items. Patients with hypertension, pain syndromes, and depression had a significantly increased risk for all sleep complaints. Patients who reported limited activity had a significant risk of restless legs syndrome. Conclusion

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“…This is consistent with other estimates of comorbidity between depression, insomnia, and obstructive sleep apnea. 6 This high concordance serves as a reminder that when primary care physicians diagnose depression, they should question their patient closely about sleep complaints, especially obstructive breathing patterns and insomnia. One weakness of this study is that it relies solely on patients' own perceptions of their diagnosis without validation by a depression scale or chart review (we plan to add this to future studies).…”

Section: Discussionmentioning

confidence: 99%

Sleeping Poorly ... and Maybe Depressed: Comorbidity in Patients Referred for Formal Sleep Studies

Sorscher¹

2007

The Journal of the American Board of Family Medicine

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Symptoms of Depression in Individuals With Obstructive Sleep Apnea May Be Amenable to Treatment With Continuous Positive Airway Pressure

Cited by 96 publications

References 29 publications

The contribution of fatigue and sleepiness to depression in patients attending the sleep laboratory for evaluation of obstructive sleep apnea

The contribution of fatigue and sleepiness to depression in patients attending the sleep laboratory for evaluation of obstructive sleep apnea

Sleep Problems in Primary Care: A North Carolina Family Practice Research Network (NC-FP-RN) Study

Sleeping Poorly ... and Maybe Depressed: Comorbidity in Patients Referred for Formal Sleep Studies

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