Symptoms of Infarction in Women: Is There a Real Difference Compared to Men? A Systematic Review of the Literature with Meta-Analysis

Cardeillac, Martin; Lefèbvre, François; Baicry, Florent; Borgne, Pierrick Le; Gil‐Jardine, Cédric; Cipolat, Lauriane; Peschanski, Nicolas; Vuillaume, Laure Abensur

doi:10.3390/jcm11051319

Cited by 6 publications

(1 citation statement)

References 34 publications

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“…In fact, most patients are unaware of their own ACS risk factors while suffering from chest pain [25][26][27]. In addition, previous studies reported that women with ACS experience different symptoms compared to that of men with ACS [18,19,22,[28][29][30]. Moreover, a study by Banco et al suggested that young women (aged ≤55 years) presenting with chest pain at the emergency department (ED) were less likely to be admitted to the hospital or to observation compared with young men [31].…”

Section: Introductionmentioning

confidence: 99%

Focused Chest Pain Assessment for Early Detection of Acute Coronary Syndrome: Development of a Cardiovascular Digital Health Intervention

Lukitasari¹,

Apriliyawan²,

Manistamara³

et al. 2023

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Background: Chest pain misinterpretation is the leading cause of pre-hospital delay in acute coronary syndrome (ACS). This study aims to identify and differentiate the chest pain characteristics associated with ACS. Methods: A total of 164 patients with a primary complaint of chest pain in the ER were included in the study. ACS diagnosis was made by a cardiologist based on the WHO criteria, and the patients were interviewed 48 hours after their admission. Furthermore, every question was analysed using the crosstabs method to obtain the odds ratio, and logistic regression analysis was applied to identify the model of focused questions on chest pain assessment. Results: Among the samples, 50% of them had an ACS. Four questions fitted the final model of ACS chest pain focused questions: 1) Did the chest pain occur at the left/middle chest? 2) Did the chest pain radiate to the back? 3) Was the chest pain provoked by activity and relieved by rest? 4) Was the chest pain provoked by food ingestion, positional changes, or breathing? This model has 92.7% sensitivity, 84.1% specificity, 85% positive predictive value (PPV), 86% negative predictive value (NPV), and 86% accuracy. After adjusting for gender and diabetes mellitus (DM), the final model has a significant increase in Nagelkerke R-square to 0.737 and Hosmer and Lemeshow test statistic of 0.639. Conclusion: Focused questions on 1) left/middle chest pain, 2) retrosternal chest pain, 3) exertional chest pain that is relieved by rest, and 4) chest pain from food ingestion, positional changes, or breathing triggering can be used to rule out ACS with high predictive value. The findings from this study can be used in health promotion materials and campaigns to improve public awareness regarding ACS symptoms. Additionally, digital health interventions to triage patients’ suffering with chest pain can also be developed.

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Section: Introductionmentioning

confidence: 99%

Focused Chest Pain Assessment for Early Detection of Acute Coronary Syndrome: Development of a Cardiovascular Digital Health Intervention

Lukitasari¹,

Apriliyawan²,

Manistamara³

et al. 2023

View full text Add to dashboard Cite

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Heart Ischemia/Reperfusion Injury—Is the Female Equally Protected Compared to Male?

Baetz,

Vedere

2023

Advances in Biochemistry in Health and Disease

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Overlooked and underserved: how healthcare fails men in the pursuit of equity

Schulz,

Ofner,

Nyirády

et al. 2024

Current Opinion in Urology

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Purpose of review Men face distinctive health-related challenges as a result of biological, behavioral, and sociocultural factors. In addition, the modern healthcare system does not offer men equal opportunities and options to ensure sex-specific access and delivery to health services. Men's health concerns are, indeed, often not addressed or even forgotten. In this review, we wanted to assess the impact of biology and sociocultural effects on sex-specific life-expectancy. Recent findings Globally, men have a shorter life expectancy than women. With a 5.8 years gender gap in the USA and 5.4 in the EU-27 (both in 2022). Cardiovascular disease, cancer, and accidents continue to represent the primary causes of mortality for both genders with all having disproportional preponderance in men. In recent years, there has been a notable decline in age-adjusted mortality rates related to cancer, while there has been an increase in deaths from accidental and intentional self-harm. Moreover, in the United States, men are more likely than women to develop and die from nonsex-specific cancers. As a result, men's poor health affects productivity, absenteeism, and employment. Summary The status of men in healthcare is complex. It is rooted in history, culture, and institutions. To address disparities, we need a comprehensive approach that includes policy reforms, sociocultural changes, and a fair and equitable public discourse. Grassroots and top-down strategies are needed to ensure a value-based societal healthcare system acknowledging the unique health needs of men.

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Symptoms of Infarction in Women: Is There a Real Difference Compared to Men? A Systematic Review of the Literature with Meta-Analysis

Cited by 6 publications

References 34 publications

Focused Chest Pain Assessment for Early Detection of Acute Coronary Syndrome: Development of a Cardiovascular Digital Health Intervention

Focused Chest Pain Assessment for Early Detection of Acute Coronary Syndrome: Development of a Cardiovascular Digital Health Intervention

Heart Ischemia/Reperfusion Injury—Is the Female Equally Protected Compared to Male?

Overlooked and underserved: how healthcare fails men in the pursuit of equity

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