The Vancouver Obsessional-Compulsive Inventory (VOCI) is a self-report inventory developed to assess a wide range of Obsessive-Compulsive symptoms. The aim of this study was to investigate psychometric properties of the Persian version of the VOCI in non-clinical samples. A questionnaire package including the VOCI, BDI-II, BAI, MOCI, OCI-R and PSWQ was administered to volunteer undergraduate students (n = 233, 139 females, 94 males) from two Iran universities (Tehran University of Medical Sciences and Allameh Tabatabaei University). All the assessments were repeated in the same sample after 2 weeks. Psychometric analyses were run to assess reliability and validity of the Persian version of the VOCI. We converged an exploratory factor analysis to test the factor structure. The VOCI-Persian had good internal consistency, test-retest reliability, convergent and divergent validity. The present study showed that the factor structure of the questionnaire consisted of five main factors: VOCI Contamination, Checking, Obsessions, Hoarding and Perfectionism/Indecisiveness. Further studies are needed to develop psychometric tools with stronger diagnostic performance for OCD assessment.