Synchronous Breast and Rectal Cancers in a Man

Karayiannakis, Anastasios J.; Kakolyris, Stylianos; Kouklakis, Georgios; Chelis, Leonidas; Bolanaki, Helen; Tsalikidis, Christos; Simopoulos, Constantinos

doi:10.1159/000328995

Cited by 10 publications

(7 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In another case, a 50-year-old man presented with symptoms of rectal adenocarcinoma. During a physical examination on one of his visits, a synchronous, asymptomatic cancer of the left breast was palpated and then diagnosed with imaging [8]. Once again, we see how proper physical examination and/or proper post-cancer imaging can help hasten the findings and thus improve the prognosis of the second primary tumor.…”

Section: Resultsmentioning

confidence: 99%

Diagnosis of Primary Colorectal Carcinoma with Primary Breast Cancer: Associations or Connections?

Weissman

Sebrow

González

et al. 2019

Cureus

View full text Add to dashboard Cite

Introduction Although once very uncommon, multiple primary malignant neoplasms (MPMN) are becoming an increasingly popular subject in medical literature. With 182,000 new diagnoses per annum, breast cancer is the most frequently diagnosed cancer amongst women in the United States. Colorectal cancer remains the second most commonly diagnosed cancer in females, and the third in males worldwide. Methods In order to gather literature on synchronous and metachronous occurring breast and colon cancer, we searched PubMed using keywords such as 'colorectal cancer', 'breast cancer', and 'MPMN'. We searched through case reports, case series, clinical trials, letters to the editor, and retrospective series. We included any manuscript in English published between January 1990 and January 2019. The articles featured patients who had primary colorectal cancer with primary breast cancer. Articles featuring patients with more than two malignancies or malignancies other than colorectal and breast cancer were excluded. Furthermore, any metastatic cancers were excluded as well. This narrowed our search down from over 100 manuscripts to just four. Results Fortunately, the prognosis was found to be no different for these patients with MPMN assuming diagnosis and treatment are performed in a timely fashion. Additionally, it appears that although a patient with one primary cancer is at a greater risk for the development of a second cancer, it is still an odd phenomenon and thus an unlikely occurrence. Conclusion Detection of one cancer increases the odds of detecting another cancer. Hence, it is important to consider the possibility of a synchronous tumor in a patient with a newly diagnosed colon tumor, as well as to not only consider disease recurrence when following up post-resection.

show abstract

Section: Resultsmentioning

confidence: 99%

Diagnosis of Primary Colorectal Carcinoma with Primary Breast Cancer: Associations or Connections?

Weissman

Sebrow

González

et al. 2019

Cureus

View full text Add to dashboard Cite

show abstract

“…Some groups opine that a less morbid surgery should be undertaken initially to complete the next surgery in a shorter time frame [ 4 ]. Simultaneous resections for both malignancies have been reported by a few [ 5 , 6 ].…”

Section: Discussionmentioning

confidence: 99%

Metastatic Sigmoid Colon Malignancy With a Synchronous Carcinoma Breast: Is Cure Possible?

Givvimani¹,

Nachiappan²,

Thota³

2022

Cureus

View full text Add to dashboard Cite

Malignancies developing in two organs or more in the same patient are called multiple primary malignancies. They can be synchronous or metachronous based on the time of diagnosis of second cancer from the first. We encountered a synchronous stage IV sigmoid colon cancer (resectable liver metastasis) and breast cancer in a lady. The clinical dilemmas that arose with multiple primary malignancies and how they were tackled in our case have been discussed. A second malignancy should not deter the management or alter the clinical decision-making. Multidisciplinary teams are crucial to the management of these rare occurrences. We could successfully manage a synchronous breast and colon cancer with resectable liver metastasis at presentation.

show abstract

“…We reported a case in which synchronous colon cancer was detected incidentally on CT scan for staging of breast cancer. Synchronous tumours have been reported to be encountered by CT and positron emission tomography (PET)-CT scans used in the staging and monitoring of malignancies 4 5…”

Section: Discussionmentioning

confidence: 99%

“…It has also been shown to confer a risk of colorectal cancer in patients with hereditary non-polyposis colorectal cancer (HNPCC) 8 10. Its function by either conferring a high risk of one cancer type and a slightly elevated risk of the other or through a predisposition to one of the two cancers and chance occurrence of the other, may help to explain synchronous occurrence of breast and colon cancer 4. Perhaps in the future such genetic testing will become applicable to patients such as in our case.…”

Section: Discussionmentioning

confidence: 99%

Synchronous breast and colon cancer: the importance of multidisciplinary team cancer meetings

2019

View full text Add to dashboard Cite

A 58-year-old female patient presented with left breast lump. Mammography and ultrasonography were performed, which reported lesions suspicious of malignancy in the left breast and axilla. Core biopsy of the lesions revealed invasive ductal carcinoma with axillary lymph node metastasis. Staging CT scan (thorax, abdomen and pelvis) identified a coexisting neoplasm in the ascending colon. Colonoscopy was performed and the tumour in the ascending colon was biopsied. Histopathological examination revealed adenocarcinoma. In the multidisciplinary team cancer meeting, it was decided to treat the breast cancer first and then the colon cancer, followed by adjuvant chemotherapy. In the first operation, left modified radical mastectomy was performed. Two weeks after her initial operation, the patient underwent laparoscopic right hemicolectomy. Postoperatively, the patient did not develop any complications and was referred to oncology for chemotherapy.

show abstract

Synchronous Breast and Rectal Cancers in a Man

Cited by 10 publications

References 18 publications

Diagnosis of Primary Colorectal Carcinoma with Primary Breast Cancer: Associations or Connections?

Diagnosis of Primary Colorectal Carcinoma with Primary Breast Cancer: Associations or Connections?

Metastatic Sigmoid Colon Malignancy With a Synchronous Carcinoma Breast: Is Cure Possible?

Synchronous breast and colon cancer: the importance of multidisciplinary team cancer meetings

Contact Info

Product

Resources

About