Synchronous carcinoma of head and neck: 2 cases report

Mardassi, Ali

doi:10.5319/wjo.v5.i2.74

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2020

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“…The etiology of multiple head and neck cancers remains unclear but several hypotheses have been suggested, including exposure to carcinogens, genetic susceptibility, immune compromisation, and initial treatments performed to address the primary cancer, causing multiple subsequent cancers [1]. Smoking and alcohol play an important role in the development of the second primary or metachronous tumors [6].…”

Section: Introductionmentioning

confidence: 99%

Triple Head and Neck Carcinoma: Case Report and Literature Review

Awad

Melibari

Safadi

et al. 2020

Cureus

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Synchronous cancers are multiple cancers that develop within six months of the initial diagnosis while metachronous cancers are those that develop more than six months after the initial diagnosis. A combination of three cancers is seen with several patients, which leads to a bad prognosis, and that of synchronous cancers is worse than that of metachronous cancers. Herein, we describe the case of a 62-year-old woman with multiple metachronous head and neck cancers.

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Section: Introductionmentioning

confidence: 99%